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1.
J Pediatr Surg ; 2024 Mar 16.
Article in English | MEDLINE | ID: mdl-38594136

ABSTRACT

INTRODUCTION: Thoracic musculoskeletal deformities are significant complications following open correction of esophageal atresia (EA) during long-term follow-up. We aimed to compare the frequency and severity of thoracic musculoskeletal deformities after open and thoracoscopic repair of EA. We hypothesized that fewer deformities would occur following the less invasive thoracoscopic approach. METHODS: This retrospective study analyzed patients treated at two pediatric surgery departments in Poland between 2005 and 2021. The patient groups differed in surgical approach, operative techniques, indications for multi-staged surgery, and postoperative complications. The study encompassed all types of EA/TEF. The first group comprised 68 patients who underwent thoracoscopic esophageal atresia repair (Wroclaw), while the second group involved 44 patients who underwent open repair (Warsaw). Clinical data were retrospectively reviewed, with results considered significant at p < 0.05. RESULTS: The median age at examination was 6 years in the thoracoscopy group and 5.5 years in the thoracotomy group. In the thoracoscopy group, 53 out of 68 patients (77.9%) and in the thoracotomy group - 35 out of 44 patients (79.5%) were treated in one stage. The incidence of thoracic musculoskeletal deformities was significantly lower in the thoracoscopy group (1.5%) compared to the thoracotomy group (34.1%, p < 0.001). Scoliosis occurred significantly more often after thoracotomy (13.6% vs 1.5%, p = 0.016). There was no rib fusion (0% vs 37.1%, p < 0.001) and no scoliosis of =>20° (0% vs 6.8%, p = 0.058) after thoracoscopy. The coincidence of rib fusion and scoliosis was significant (9.1%, p = 0.022) for the open approach. In the thoracotomy group, multi-staged surgery and more frequent reoperations due to major complications were significantly associated with an increased occurrence of deformities. None of the patients after thoracoscopic multi-stage or complicated EA/TEF repair developed scoliosis. CONCLUSIONS: The frequency and severity of thoracic musculoskeletal deformities were significantly lower after the thoracoscopic approach. Thoracoscopy may be a more advantageous and preferred surgical approach for the EA/TEF treatment, although further randomized, controlled studies are necessary. Post-thoracotomy scoliosis may progress to a severity requiring surgery.

2.
Arch Med Sci ; 17(4): 1128-1131, 2021.
Article in English | MEDLINE | ID: mdl-34336042

ABSTRACT

INTRODUCTION: The aim of the study was to examine management of pediatric appendiceal neuroendocrine tumors (ANETs) in Poland. METHODS: Records of 27 patients with ANET diagnosed incidentally after appendectomy in the last decade. RESULTS: Well-differentiated NET G1/G2 was diagnosed in 25 and well-differentiated neuroendocrine carcinoma G3 in 2 patients. Extended surgery was performed primarily in one instance and secondarily in 10 patients (right hemicolectomy in 9, ileocecal resection in 1) without adjuvant chemotherapy. Follow-up range was 1-121 months. Recurrence after secondary surgery was observed in 1 (3.7%) patient. CONCLUSIONS: Applying ENETS guidelines resulted in 100% overall survival of patients with NET.

3.
Pediatr Med Chir ; 43(1)2021 Feb 22.
Article in English | MEDLINE | ID: mdl-33666066

ABSTRACT

Congenital Diaphragmatic Hernia (CDH) occurs in 1:4000 live births. It's morbidity and mortality rates are significant. Recurrence is one of the recognized complications occurring after a successful initial repair. Poorly known are the rate of recurrence and factors that may influence the re-herniation. Poorly described are its morphology and treatment. Medical records of 95 neonates with CDH who had undergone repair at tertiary pediatric teaching hospital between 2007-2018 were retrospectively reviewed. Prior to surgery, peri-operative and recurrence data were collected. The follow-up was 1 to 12 years after the initial repair. Recurrence occurred in 22/84 (26%) patients. In 5 patients we observed more than one recurrence, total number of 27 (32%) re-herniations; 16/22 (72%) recurrences occurred within first 12 months; 7/27 (26%) recurrences were symptomatic which gives the symptomatic recurrence rate 8.3%; 20/27 (74%) were asymptomatic. There were no significant differences between groups considering LHR, gestational age, birth weight, severity of pre-surgery and post-surgery stabilization period. Significantly higher Apgar scores were in the group without recurrence. Among subjects with recurrent CDH majority had a left-sided defect, no hernia sac, no liver herniation, diaphragm was primarily sutured, abdominal wall primarily closed. Even though none of those factors was significantly related with the recurrence. Recurrence in CDH remains a significant issue for long-term surgical morbidity, especially more apparent in the first year of life. As long as the risk factors of re-herniation remains unclear, the most important seems to be routine follow-up protocol allowing for CDH recurrence detection.


Subject(s)
Hernias, Diaphragmatic, Congenital , Child , Gestational Age , Hernias, Diaphragmatic, Congenital/epidemiology , Hernias, Diaphragmatic, Congenital/surgery , Humans , Infant, Newborn , Recurrence , Retrospective Studies , Risk Factors
4.
Psychiatr Pol ; 50(1): 127-43, 2016.
Article in English, Polish | MEDLINE | ID: mdl-27086333

ABSTRACT

Trichotillomania is a disorder characterised by inability to control over pulling own hair from various parts of a body resulting in noticeable hair loss. Due to its long-term, progressive course, untreated trichotillomania can lead to disturbances in the functioning of patients and complications which are dangerous to life and health. Due to the ambiguous nature of the symptoms, they often remain unrecognised by clinicians. Most patients are afraid of revealing symptoms and reluctantly seek for professional help. In our opinion, it is necessary to increase the awareness of the disorder of physicians of different specialties to improve the detection, treatment efficacy and to prevent dangerous complications of trichotillomania. This paper summarises the current state of knowledge on the epidemiology, aetiology, clinical presentation, and treatment of trichotillomania. It is also an attempt to create guidelines in all cases of suspected trichotillomania - adapted to Polish conditions. It also highlights the importance of a multidisciplinary treatment as a condition of effectiveness of the therapy and prevention of relapse.


Subject(s)
Self-Injurious Behavior/diagnosis , Self-Injurious Behavior/therapy , Trichotillomania/diagnosis , Trichotillomania/therapy , Behavior Therapy/methods , Female , Humans , Male , Poland , Psychotherapy , Psychotropic Drugs/therapeutic use , Self-Injurious Behavior/psychology , Trichotillomania/psychology
5.
Psychiatr Pol ; 50(1): 145-52, 2016.
Article in English, Polish | MEDLINE | ID: mdl-27086334

ABSTRACT

AIM: Trichotillomania is a lack of control of one's hair pulling. It is estimated that about 1% of population develops trichotillomania. In up to 20% of patients with trichotillomania swollowing follows hair pulling. Trichobezoar forms in about 30% of patients with trichofagia. MATERIAL AND METHODS: In 2008-2014 3 patients were operated on trichobezoar. One patient has had a history of trichotillomania. On admission abdominal X-ray and ultrasonography revealed abdominal mass. Diagnosis was confirmed in abdominal computed tomography. RESULTS: All three trichobezoars were evacuated from the intestinal tract during laparotomy with wide gastric wall opening. In one case - Rapunzel syndrome - hair mass was evacuated also from the duodenum and small bowel. All patients were referred to psychiatrist after finishing of the surgical treatment. CONCLUSIONS: In patients operated for trichobezoar as well as other patients with trichotillomania control of hair accumulation in the gastrointestinal tract remains a problem. Authors propose endoscopic follow up scheme in 6, 12, and 24 months after the surgery as well as for other patients with trichotillomania.


Subject(s)
Bezoars/surgery , Gastroscopy/methods , Trichotillomania/surgery , Adolescent , Female , Follow-Up Studies , Humans , Male
6.
Eur J Haematol ; 96(6): 637-42, 2016 Jun.
Article in English | MEDLINE | ID: mdl-26268883

ABSTRACT

Splenectomy is considered standard surgical therapy in hereditary spherocytosis. The procedure is indicated in patients with severe anemia, recurrent hemolytic, and aplastic crises. The aim of the study was to assess treatment outcomes in patients with hereditary spherocytosis who underwent total or partial laparoscopic splenectomy. Fifteen patients aged 4-17 yr underwent laparoscopic splenectomy from 2009 to 2012. Partial and total splenectomies were performed (five and 10 children, respectively). Hematologic parameters, liver function tests, and splenic volume before and after the surgery were analyzed retrospectively. Total follow-up was 1-30 months. Hospitalization and operating time were similar in both groups. In partial splenectomy group, branches of splenic arteries gave better blood supply than short gastric vessels. In both groups, hematologic parameters were improved. Postoperative markedly elevated platelet count was maintained up to 6 months, and after that, platelet count gradually decreased to normal values. Bilirubin level was decreased in early postoperative period; however, it increased later to achieve levels lower than in preoperative period. No severe general infections were observed in both groups. Laboratory parameters (hemoglobin and bilirubin concentrations and RBC) after the surgery improved in all patients, and the effect was maintained during 12 months of follow-up. Platelet count increased significantly after the surgery and was maintained at high levels during the next 6 months. However, it returned to preoperative levels within a year after the surgery. Our study showed that partial splenectomy was not inferior to total splenectomy. However, full assessment requires longer follow-up and larger group of patients.


Subject(s)
Laparoscopy/methods , Spherocytosis, Hereditary/surgery , Splenectomy/methods , Adolescent , Bilirubin/blood , Child , Child, Preschool , Erythrocyte Indices , Female , Humans , Laparoscopy/adverse effects , Length of Stay , Male , Operative Time , Platelet Count , Spherocytosis, Hereditary/diagnosis , Splenectomy/adverse effects , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, Doppler
7.
Adv Med Sci ; 61(1): 18-22, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26344909

ABSTRACT

PURPOSE: Anorectal 3-dimensional high definition manometry (3D HRM) could be the best tool for postoperative assessment of restorative surgical procedures for Hirschsprung's disease. The aim of our study was to evaluate patients after surgery for Hirschsprung's disease using 3D HRM. MATERIALS AND METHODS: Anorectal function was evaluated using solid state 3D HRM. We measured the length of the anal canal, mean resting squeeze pressures, the presence of rectoanal inhibitory reflex, cough reflex, ano-anal reflex and the bear down manoeuvre. RESULTS: We studied 14 children operated on for Hirschsprung's disease. The mean values of pressure asymmetry were higher in patients after the Duhamel procedure than after the TEPT procedure (29.58% vs. 22.26% during resting and 26.1% vs. 14.01% during squeeze, respectively). No difference between the groups was observed in the measurement of all the manometric parameters except the presence of rectoanal inhibitory reflex (87.5% after TEPT vs. 33% after Duhamel). CONCLUSIONS: Anorectal 3D HRM evaluation of patients with Hirschsprung's disease demonstrated that the asymmetry of the anal canal occurred in a similar percentage after both procedures.


Subject(s)
Hirschsprung Disease/physiopathology , Hirschsprung Disease/surgery , Imaging, Three-Dimensional , Manometry/methods , Adolescent , Anal Canal/physiopathology , Catheters , Child , Child, Preschool , Feces , Female , Humans , Infant , Male , Pilot Projects , Pressure , Treatment Outcome
8.
J Med Case Rep ; 9: 268, 2015 Nov 20.
Article in English | MEDLINE | ID: mdl-26585230

ABSTRACT

INTRODUCTION: Solid pseudopapillary tumor of the pancreas is extremely rare in children; it usually occurs in young women between 18 and 35 years of age. It comprises less than 3% of pancreatic tumors. It is of low malignancy; however, it may be locally aggressive. Surgical resection is the treatment of choice and its prognosis is excellent. CASE PRESENTATION: Two Caucasian girls, 15 and 12 years of age were diagnosed with tumor of the pancreas. The first patient had severe abdominal pain. In the second case the tumor was asymptomatic, detected incidentally during ultrasound. Computed tomography confirmed pancreatic mass. In the first case, apart from the tumor located in the head and the body of her pancreas, focal change in her right kidney was found, which was an indication to biopsy that confirmed solid pseudopapillary tumor. In the second patient the tumor was located in the body of her pancreas, with portal vein occlusion and well-developed collateral circulation. In the first patient a pancreatoduodenectomy (Traverso-Longmire) was performed; there was no mass in her right kidney. In the second case, distal pancreatectomy and splenectomy were performed. In both cases histopathology revealed solid pseudopapillary tumor resected radically. Our first patient's postoperative course was uneventful. In the second case, her postoperative course was complicated by necrosis of the remaining pancreatic head that needed pancreatoduodenectomy. Follow-up at 28 and 26 months revealed no evidence of tumor recurrence or metastases on magnetic resonance imaging. CONCLUSIONS: Typical radiological appearance of solid pseudopapillary tumor is an indication for surgery. The treatment of choice is tumor resection with sparing of pancreatic tissue. In one of our two cases we performed a preoperative biopsy because of an uncharacteristic mass in her right kidney. In our second patient, necrosis of her spared pancreatic head meant that we could not preserve pancreatic tissue. Our whole diagnostic process, treatment and possible complications analysis should be of interest and noteworthy not only to surgeons as the treatment of choice is radical resection, but also to pediatric oncologists because of differentiation from other pancreatic tumors in children.


Subject(s)
Abdominal Pain/etiology , Neoplasm Recurrence, Local/pathology , Pancreatic Neoplasms/diagnosis , Pancreatic Pseudocyst/diagnosis , Adolescent , Child , Female , Humans , Pancreatectomy , Pancreatic Neoplasms/pathology , Pancreatic Neoplasms/surgery , Pancreatic Pseudocyst/pathology , Pancreatic Pseudocyst/surgery , Prognosis , Splenectomy , Tomography, X-Ray Computed , Treatment Outcome
9.
J Med Case Rep ; 9: 104, 2015 May 06.
Article in English | MEDLINE | ID: mdl-25943401

ABSTRACT

INTRODUCTION: Desmoid tumor is a rare, benign, usually asymptomatic fibromatous lesion. The etiology is unknown and the diagnosis is based on histopathological examination. The treatment is complete resection of the tumor. Pancreatic desmoid tumor is extremely rare. In the literature there have been only 11 cases described, most of them as solid or solid-cystic masses. We report the case of a patient with an isolated cystic pancreatic desmoid tumor that is, to the best of our knowledge, the second reported case. CASE PRESENTATION: A 13-year old Caucasian boy presented with recurrent pain of two months' duration in the left hypochondrium of his abdomen. An ultrasound examination and computed tomography scan revealed the presence of a cystic mass located in his splenic hilum, tightly adjacent to the pancreatic tail. A splenic cyst was suspected. Operative findings showed a 10 x 10 cm cystic mass tightly connected to the pancreatic tail and left colonic flexure, adherent to the spleen, splenic vein and artery. Distal splenopancreatectomy with en bloc resection of the left colonic flexure was performed. Histological analysis confirmed that the resection was complete. The mass had infiltrated the pancreatic parenchyma. All tumor cells were positive for anti-beta-catenin staining characteristic for desmoid tumor. No abnormalities in the spleen and colon were found. CONCLUSIONS: Isolated sporadic pancreatic desmoid tumor with cyst formation is extremely rare and its diagnosis can be difficult, especially because of uncharacteristic symptoms and radiological findings, as in our patient. This case report should be of interest not only to surgeons, as the treatment of choice is radical resection, but also gastroenterologists, considering it is in close relation with familial adenomatous polyposis, and oncologists as the reason for differentiation with other pancreatic tumors.


Subject(s)
Fibromatosis, Aggressive/diagnosis , Pancreas/pathology , Pancreatic Neoplasms/diagnosis , Adolescent , Diagnosis, Differential , Humans , Immunohistochemistry , Male , Tomography, X-Ray Computed
10.
Dev Period Med ; 19(3 Pt 1): 283-8, 2015.
Article in English | MEDLINE | ID: mdl-26958691

ABSTRACT

UNLABELLED: The predicitive values of fetal ultrasonography and magnetic resonance imaging are well established as antenatal outcome predictors in neonates with congenital diaphragmatic hernia (CHD). Postnatal outcome predictors remain elusive. THE AIM: To evaluate the value of the oxygenation index (OI) as a predictor of postnatal survival. MATERIAL AND METHODS: 58 newborns with congenital diaphragmatic hernia, treated in the same centre (a university hospital) between February 2006 and March 2014 were involved in the retrospective study. Standardized preoperative stabilization involved: sedation without muscle paralysis, high frequency oscillation ventilation (HFOV) and inhaled nitric oxide (iNO, used as required). Oxygenation index OI = FiO2 x 100 x M AP/PaO2, where FiO2 is the fraction of inspired oxygen, MAP is the mean airway pressure, and PaO2 is the partial pressure of oxygen in arterial blood, calculated at the end of the first day of standardized preoperative stabilization, and evaluated as a predictor of survival. RESULTS: The overall survival rate on the hospital discharge was 74.1%. As far as the oxygenation index (OI) at the end of the first day of the preoperative stabilisation is concerned, in 40/43 survivors it was below or equal to 12, in one infant it equalled 12.7, and in two remaining survivors OI was much higher (18 and 56, respectively). The prognostic value of the oxygenation index was high, with the area under the curve (AUC) 0.943, sensitivity 0.930, and specificity 0.876. CONCLUSIONS: The oxygenation index (OI) calculated at the end of the first day of standardized preoperative stabilization with high frequency oscillation ventilation (HFOV) and nitric oxide (iNO) is a simple and sensitive predictor of the survival of neonates with a congenital diaphragmatic hernia. It may be a valuable tool to select high-risk neonates who might require more invasive therapeutic modalities, i.e. extracorporeal membrane oxygenation (ECMO).


Subject(s)
Extracorporeal Membrane Oxygenation , Hernias, Diaphragmatic, Congenital/diagnosis , Hernias, Diaphragmatic, Congenital/therapy , High-Frequency Ventilation , Oxygen/metabolism , Blood Gas Analysis , Female , Humans , Infant , Infant, Newborn , Male , Predictive Value of Tests , Prognosis , Retrospective Studies , Survival Rate
12.
Ortop Traumatol Rehabil ; 16(1): 11-6, 2014.
Article in English | MEDLINE | ID: mdl-24728790

ABSTRACT

BACKGROUND: In Germany, rates of primary total knee arthroplasty procedures and exchange arthroplasty procedures continue to rise. Late-onset peri-prosthetic infection constitutes a serious complication whose management may be dependent upon the spectrum of micro-organisms involved. The aim of this study was to provide a retrospective analysis of the effectiveness of initial eradication measures performed as part of a two-stage procedure. MATERIAL AND METHODS: Between 2002 and 2008, a total of 328 patients who had received a first-time diagnosis of chronic peri-prosthetic knee infection following total knee arthroplasty (TKA) subsequently underwent surgery at our clinic. The surgical approach consisted of a two-stage procedure, with the initial procedure consisting of the removal of the prosthesis and radical debridement, followed by insertion of an antibiotic-loaded static spacer. The effectiveness of the procedure was assessed after six weeks, with each patient undergoing a number of clinical and laboratory-based tests, including knee joint aspiration. RESULTS: Staphylococcus aureus strains were responsible for 68% (n=223) of the total number of cases of peri-prosthetic knee infection. 19% of cases (n=62) showed evidence of gram-negative bacteria, while MRSA accounted for 15% (n=49) of cases. Six weeks after completion of the above-named treatment regimen, eradication of infection was considered successful in 289 patients (88.1%). Eradication was unsuccessful in 22% of MRSA infections (n=11) and 7% of MSSA infections (n=23). CONCLUSION: The treatment regimen outlined in this report is capable of achieving satisfactory results in the management of late-onset peri-prosthetic knee infection, with one exception: patients with infections caused by MRSA showed high failure rates.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Arthroplasty, Replacement, Knee/adverse effects , Bacterial Infections/drug therapy , Bone Cements , Prosthesis-Related Infections/prevention & control , Adult , Arthroplasty, Replacement, Knee/methods , Drug Resistance, Multiple, Bacterial , Female , Germany , Humans , Knee Prosthesis/adverse effects , Knee Prosthesis/microbiology , Male , Middle Aged , Prosthesis-Related Infections/surgery , Retrospective Studies
13.
Langenbecks Arch Surg ; 397(1): 117-23, 2012 Jan.
Article in English | MEDLINE | ID: mdl-21913007

ABSTRACT

PURPOSE: The aim of this study was to assess the incidence of methicillin-resistant Staphylococcus aureus (MRSA) colonisation in patients admitted into a level 1 German trauma centre with proximal femur fractures, to correlate this incidence with defined risk factors for MRSA colonisation and to determine its influence on morbidity and mortality. METHODS: Between August and November 2006, 65 patients were included in the study. Cotton-tipped swab samples were taken from the nose, throat, groin and any skin defects in the emergency room. The following factors were recorded: age, gender, any concomitant diseases, the fracture type and treatment device, skin lesions, hospitalisation within the last year, any urinary or vascular catheters, a nasogastric or gastrostomy tube, an ileal stoma, the use of a respirator and antibiotic therapy within the last year. During follow-up, data concerning any surgical site infections; any chest, urinary or vascular catheter infections; the success of decontamination and death within 1 year after surgery were collected. RESULTS: The risk factors for MRSA colonisation were positive in 40 patients. The incidence of MRSA colonisation was 17%, which is higher than in most comparable studies but consistent with some very recent publications. The nosocomial infection rates, surgical site infection rates and mortality within the 1-year follow-up period were significantly higher in the MRSA-colonised patients. CONCLUSION: The high incidence of MRSA in this study supports the need for systematic detection of MRSA-colonised patients. In our hospital, any patient with positive risk factors for MRSA colonisation is swabbed in the emergency room and treated as MRSA positive until proven otherwise.


Subject(s)
Hip Fractures/microbiology , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Aged, 80 and over , Cross Infection/transmission , Female , Femoral Neck Fractures/microbiology , Femoral Neck Fractures/surgery , Hip Fractures/surgery , Hospitalization , Humans , Male , Risk Factors , Staphylococcal Infections/complications , Staphylococcal Infections/transmission , Trauma Centers
14.
Ortop Traumatol Rehabil ; 11(4): 360-5, 2009.
Article in English | MEDLINE | ID: mdl-19828918

ABSTRACT

The treatment of septic bone defects represents a significant challenge in orthopaedic surgery. Non-vascularised cancellous bone grafts are very commonly used. In contrast, thin and malleable periosteal grafts have generally only been investigated in animal models. The free corticoperiosteal flap is used only in exceptional cases in traumatology. This case report describes the treatment of an infected and non-reactive bone defect in the shaft of the tibia. This case involves a septic non-union over two years old with evidence of methicillin-resistant Staph. aureus. A vascularised corticoperiosteal flap was used to bridge this defect. The procedure was supplemented by rigid internal fixation. There were no postoperative complications. Bone healing was documented eleven months after the described treatment. No further invasive procedures were required. The patient was able to return to his original occupation as a store manager. Stable internal fixation is an important precondition for successful treatment. The method described in this article can be considered for short defects when a conventional cancellous bone graft appears to be contraindicated.


Subject(s)
Fracture Fixation, Internal/methods , Fractures, Ununited/surgery , Methicillin-Resistant Staphylococcus aureus , Staphylococcal Infections/therapy , Surgical Flaps , Surgical Wound Infection/surgery , Tibial Fractures/surgery , Adult , Bone Transplantation/methods , Female , Fractures, Ununited/microbiology , Humans , Staphylococcal Infections/microbiology , Surgical Wound Infection/microbiology , Tibial Fractures/microbiology , Treatment Outcome
15.
Int J Hyg Environ Health ; 212(2): 209-15, 2009 Mar.
Article in English | MEDLINE | ID: mdl-18667356

ABSTRACT

Meticillin-resistant Staphylococcus aureus (MRSA) are endemic in hospitals worldwide and present a major concern in hospital hygiene. The aim of the present study was to investigate the relationship between patients' MRSA colonization of the body and the frequency of environmental contamination. Twenty-five MRSA-positive hospitalized surgical patients and their environment in isolation rooms were screened on four occasions over a 14-day period. Out of 1099 samples from patients, 330 (30.0%) were MRSA-positive. The median number of MRSA-positive body sites per screening decreased significantly from the 1st (3, range 1-9) to the 14th (2, range 0-9, p=0.011) day of isolation. Contamination was found in 45% of the 100 environmental sampling dates and MRSA was detected in a low proportion of the 1000 environmental surface samples: 105/1000 (10.5%). The number of positive results for each sampling date decreased from the 1st (median 1, range 0-8) to the 14th (median 0, range 0-3, p=0.21) day of isolation. The results show a very strong correlation between the number of MRSA-positive body sites of individual patients and the MRSA contamination of the patient's hospital room (r=0.700, p<0.001). Pulsed-field gel electrophoresis (PFGE) analysis demonstrated a 98% agreement between patient and environmental samples. MRSA colonization of the groin area correlates most strongly with colonization of the body and environment. Seventy-five of 240 (31%) samples taken in rooms of patients with colonization of the groin were MRSA-positive, whereas only 27 of 760 (3.6%) samples taken in rooms of patients without colonization of the groin produced positive results (odds ratio 12.3; 95% confidence interval, 7.7-20). It is concluded that MRSA patients without colonization of the groin have a relatively low risk of environmental spread of MRSA and thus a reduced risk of transmission.


Subject(s)
Cross Infection/transmission , Disease Reservoirs/microbiology , Methicillin-Resistant Staphylococcus aureus , Patient Isolation , Staphylococcal Infections/transmission , Adult , Aged , Aged, 80 and over , Carrier State/microbiology , Cross Infection/microbiology , Environmental Monitoring , Equipment Contamination , Female , Groin/microbiology , Humans , Infection Control , Male , Middle Aged , Odds Ratio , Staphylococcal Infections/microbiology
16.
Acta Orthop Belg ; 74(2): 235-9, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18564482

ABSTRACT

Five patients with atrophic or septic non-union of long bones were treated with free vascularised corticoperiosteal bone flaps. The patients had undergone an average of nine prior operations (range, 2-29). The treatment was combined with repeat internal fixation in four patients,. Treatment took place an average of 25.5 months (range 5-83 months) after the initial injury. The thin corticoperiosteal grafts were harvested from the supracondylar region of the femur. One patient died from unrelated causes 2.5 months postoperatively. In the other four patients, bone healing was documented after an average of 7.7 months (range 6-11 months). No further operations were necessary during the follow-up period of 13.7 months on average (range 10-17 months). There were no complications associated with the procedure. The treatment presented here is complex but was successful in this small population. The procedure has the potential to become established as a treatment option for problematic bone defects.


Subject(s)
Bone Transplantation/methods , Fractures, Ununited/surgery , Adult , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Surgical Flaps , Transplantation, Autologous , Treatment Outcome
17.
Acta Orthop Belg ; 74(1): 102-8, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18411609

ABSTRACT

The treatment of atlantoaxial instability by means of posterior transarticular screw fixation combined with a Gallie fusion is an established method when direct anterior odontoid screw fixation is not indicated or has failed. In this retrospective study, the results of a modified percutaneous mini-open transarticular C1-C2 screw fixation are presented. Between February 1998 and March 2006, 47 patients with acute or late (after failed conservative treatment) atlantoaxial instability were treated with the modified technique. Their average age was 74.9 years. There were no intraoperative injuries to neural structures or blood vessels; 96.8% of the screws were placed correctly. A revision operation was necessary in one patient because of infection at the graft donor site. No patient experienced a neurological complication. Three patients died during hospitalisation, 6 others later on; 6 could not be traced, leaving thirty-two patients or 68% available for follow-up. The average clinical follow-up was 42 months (range: 12 to 91). The results with respect to the pain and activity status were good or excellent in more than 90% of cases. The radiographic follow-up averaged 25 months (range: 12 to 75). Bony fusion was documented in all cases. The modified technique of transarticular screw fixation presented here is a safe and functionally satisfactory method of achieving stabilisation of the atlantoaxial complex. Special cannulated instruments are not required. This mini-open transcutaneous technique is an alternative to the conventional open procedure, and reduces operation time as well as blood loss.


Subject(s)
Atlanto-Axial Joint , Bone Screws , Joint Instability/surgery , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Atlanto-Axial Joint/diagnostic imaging , Female , Humans , Male , Middle Aged , Postoperative Complications , Radiography , Reoperation , Retrospective Studies , Treatment Outcome
18.
Med Wieku Rozwoj ; 12(4 Pt 2): 1051-5, 2008.
Article in Polish | MEDLINE | ID: mdl-19531825

ABSTRACT

The incidence of pancreatitis in patients with haematopoetic neoplasms who are treated with L-asparaginase is fom 2 to 24%. In majority of cases the pancreatitis is oedematous and self-limiting. Acute haemorrhagic or necrotizing pancreatitis caused by L-asparaginase is rare but potentially life-threatening complication. We present 2 cases of acute pancreatitis in children aged 2 and 4 years. They were diagnosed to have acute lymphoblastic leukaemia and were treated according to the ALLLIC BFM 2002 protocol. Acute pancreatitis developed in these children after induction therapy and was followed by formation of a pseudocyst. In both cases the diagnosis of this complication was made directly after phase I of the protocol I (after eighth dose of L-Asparaginase). In the first case the course of acute pancreatitis was mild. Normalization of the amylase levels occurred after 7 days and the diagnosis of post inflammatory cyst was made 15 days after the first signs of the disease. But thereafter, during the additional complication (pneumonia with Pseudomonas aeruginosa bacteriemia) the pancreatic cyst became infected. In the second case acute pancreatitis had a severe course and the child required treatment in the Intensive Care Unit for 21 days. The cyst was diagnosed after 20 days from the beginning of symptoms. The surgical procedure, applied in both cases was internal drainage by anastomosis of the cyst with the back wall of the stomach. Antileukaemic treatment was recommenced after 6-8 weeks when complications resolved. Currently both children are well and remain in haematological remission and continue maintenance chemotherapy.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/adverse effects , Pancreatic Pseudocyst/complications , Pancreatitis/etiology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Acute Disease , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Asparaginase/administration & dosage , Asparaginase/adverse effects , Asparaginase/therapeutic use , Child, Preschool , Daunorubicin/adverse effects , Daunorubicin/therapeutic use , Drainage , Female , Humans , Pancreatic Pseudocyst/diagnosis , Pancreatic Pseudocyst/therapy , Pancreatitis/diagnosis , Pancreatitis/therapy , Prednisone/adverse effects , Prednisone/therapeutic use , Vincristine/adverse effects , Vincristine/therapeutic use
19.
Ortop Traumatol Rehabil ; 9(6): 599-603, 2007.
Article in English | MEDLINE | ID: mdl-18227751

ABSTRACT

BACKGROUND: The aim of the study was to present the results of fenestration arthroscopy in five patients with primary septic arthritis of the hip. MATERIAL AND METHODS: The mean follow-up period was 52 months. Gram staining and the leukocyte count of the preoperative joint fluid and the systemic CRP level were of particular importance in confirming the diagnosis. In all five cases, the causative germ was a gram-positive coccus. The operative procedure and postoperative treatment were the same. A mini-arthrotomy was performed through a modified Watson-Jones approach. Following fenestration of the anterior tense capsule, arthroscopic inspection of the joint took place with continuous irrigation. RESULTS: Postoperative recovery was rapid in all patients. The antibiotic treatment was continued for four weeks post-intervention. No complications occurred. At follow-up all patients were asymptomatic and had no restriction in the function of the affected hip. CONCLUSIONS: Taking the discussed contraindications into account, fenestration arthroscopy represents a useful alternative to the established open procedure in septic arthritis of the hip. Important determinants of successful treatment are absence of involvement of the bone and cartilage and intervention as soon as possible.


Subject(s)
Arthritis, Infectious/surgery , Arthroscopy/methods , Gram-Positive Bacterial Infections , Hip Joint/surgery , Adult , Female , Follow-Up Studies , Hip Joint/microbiology , Humans , Male , Treatment Outcome
20.
Wiad Lek ; 59(1-2): 131-4, 2006.
Article in Polish | MEDLINE | ID: mdl-16646310

ABSTRACT

Amanita phalloides poisoning is one of the most dramatic medical invents. The course of the illness may vary from mild to the lethal, with signs of fulminant liver insufficiency with coma and multiorgan failure. When hepatic encephalopathy (III/IV degrees) occurs the prognosis is very poor. In definite cases the liver transplantation is necessary. The authors present severe Amanita phalloides poisoning in three family members, who due to fulminant hepatic failure underwent liver transplantation. The two of them (son and father) transplanted accordingly in fifth and seventh day after poisoning, survived. Mother, in whom transplantation started in ninth day after poisoning, died intraoperativel with signs of massive hemorrhage, and cardiac arrest.


Subject(s)
Amanita , Hepatic Encephalopathy/etiology , Liver Failure/etiology , Liver Failure/surgery , Liver Transplantation , Mushroom Poisoning/complications , Adolescent , Adult , Female , Humans , Male
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