1.
Org Lett
; 25(49): 8932-8936, 2023 Dec 15.
Article
in English
| MEDLINE
| ID: mdl-38049370
ABSTRACT
A copper-catalyzed chemo- and stereoselective method for the synthesis of (E)-2-silyl-1,3-butadienes from a broad range of allenols using mild Si-B reagents is reported in this study. Our protocol required a short reaction time at ambient temperature to produce the desired dienes in high yields. Synthetic applications are highlighted by the one-pot synthesis of tetrasubstituted arylsilanes from allenols as well as the further functionalization of C-Si bonds.