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Bull Exp Biol Med ; 139(3): 290-2, 2005 Mar.
Article in English, Russian | MEDLINE | ID: mdl-16027833

ABSTRACT

We studied acception of cholesterol from Fu5AH hepatoma cells by blood serum from subjects with normal level of high-density lipoprotein cholesterol and hyperlipidemia (alone or in combination with other risk factors for coronary heart disease). Cholesterol-binding activity of high-density lipoproteins decreased in subjects with hyperlipidemia alone or in combination with excess body weight and/or arterial hypertension. Impairment of high-density lipoprotein activity was associated with changes in their phospholipid composition.


Subject(s)
Cholesterol, HDL/metabolism , Coronary Disease/etiology , Coronary Disease/prevention & control , Adult , Blood Pressure , Body Mass Index , Body Weight , Carcinoma, Hepatocellular/metabolism , Cholesterol/blood , Cholesterol/metabolism , Cholesterol, HDL/blood , Coronary Disease/blood , Humans , Hyperlipidemias/complications , Liver Neoplasms/metabolism , Male , Middle Aged , Risk Factors , Tumor Cells, Cultured , Urban Population
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