ABSTRACT
Data on DPA side effects were gathered from six schools and colleges of optometry for a reporting period from February 1 to April 30, 1979. These data indicate a low incidence of mild and transient side effects caused by several of the DPAs.
Subject(s)
Anesthetics, Local/adverse effects , Mydriatics/adverse effects , Ophthalmic Solutions/adverse effects , Optometry , Chlorobutanol/adverse effects , Cyclopentolate/adverse effects , Drug Combinations/adverse effects , Edetic Acid/adverse effects , Fluoresceins/adverse effects , Humans , Phenylephrine/adverse effects , Povidone/adverse effects , Procaine/adverse effects , Procaine/analogs & derivatives , Propoxycaine/adverse effects , Rose Bengal/adverse effects , Tropicamide/adverse effectsABSTRACT
Potentially pathogenic yeast strains from four genera, Candida, Cryptococcus, Torulopsis, and Trichosporon, were examined for killer activity and sensitivity using Saccharomyces and Torulopsis strains of known killer status. Tests were performed by using a streak method and by concentration of culture fluid by lyophilization. Of 236 strains examined, killers were found with low prevalence among Torulopsis and Cryptococcus strains; Candida and Trichosporon isolates showed no killing activity. Different specificities of killing activity were observed among strains of a single species. Sensitive strains were found with varying frequencies in all genera but Trichosporon.
Subject(s)
Yeasts/physiology , Candida/physiology , Microbial Sensitivity Tests , Mycotoxins/biosynthesis , Mycotoxins/pharmacology , Saccharomyces/physiology , Species SpecificityABSTRACT
The double-stranded RNA content, the production of inactive killer protein, and the presence of virus-like particles were examined in induced nonkiller mutants and nonkiller progeny from a cross between a killer strain and a sensitive strain. A correlation between the loss of the 0.7 x 10(6) daltons dsRNA of the Ustilago maydis P6 virus and the lack of synthesis of the killer protein was established. In vitro and in vivo complementation between nonkiller strains provide additional support for the suggestion that the 0.7 x 10(6) daltons dsRNA is related to the killer function. The coding capacity of the various species of dsRNA is discussed in relation to their possible function.
