ABSTRACT
140 patients with brain tumor were treated by CT-guided stereotactic injections of radionuclides, such as Aurum-198 (198 Au), Phosphorus-32 (32 P) and Yttrium-90 (90Y). Of these patients aged from 3 to 67 years (average 37), 64 were male and 76 female. Astrocytoma was found in 75 patients, craniopharyngioma in 46, metastatic carcinoma in 7, meningioma in 5, germinoma in 4 and pituitary adenoma in 3. The tumors were located in the deep part or functionally critical area of the brain. After 267 times of injection of colloidal isotopes, no major adverse effects or complications occurred. Follow-up for 6 to 48 months showed improvement in symptoms in 104 (74.3%) patients and CT scanning showed the diminished tumors.
Subject(s)
Astrocytoma/radiotherapy , Brain Neoplasms/radiotherapy , Craniopharyngioma/radiotherapy , Adolescent , Adult , Aged , Brachytherapy/methods , Child , Child, Preschool , Female , Glioblastoma/radiotherapy , Gold Radioisotopes/therapeutic use , Humans , Male , Middle Aged , Phosphorus Radioisotopes/therapeutic use , Stereotaxic Techniques , Tomography, X-Ray Computed , Yttrium Radioisotopes/therapeutic useABSTRACT
The authors report on 40 brain tumor patients treated with CT-guided stereotactic injection of 198Au and 32P. Among the 40 cases were astrocytoma in 23 cases, craniopharyngioma in 9, meningioma in 4, pituitary adenoma in 2, and pinealoma and metastatic carcinoma each in 1 case. The tumors were all located in deep or important areas of the brain which were difficult to deal with by conventional operation. 62 injections of colloidal isotopes were performed, and all were successful. No major adverse effects or complications occurred on follow-up of 6-12 months, 28 patients were improved in their clinical symptoms, and CT scanning showed that the tumor sizes were diminished. The effective rate is 70%.
Subject(s)
Brain Neoplasms/radiotherapy , Brain Neoplasms/surgery , Gold Radioisotopes/therapeutic use , Phosphorus Radioisotopes/therapeutic use , Radiosurgery/methods , Adenoma/diagnostic imaging , Adenoma/radiotherapy , Adenoma/surgery , Adult , Astrocytoma/diagnostic imaging , Astrocytoma/radiotherapy , Astrocytoma/surgery , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/secondary , Craniopharyngioma/diagnostic imaging , Craniopharyngioma/radiotherapy , Craniopharyngioma/surgery , Female , Gold Radioisotopes/administration & dosage , Humans , Male , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/radiotherapy , Meningeal Neoplasms/surgery , Meningioma/diagnostic imaging , Meningioma/radiotherapy , Meningioma/surgery , Phosphorus Radioisotopes/administration & dosage , Pinealoma/diagnostic imaging , Pinealoma/radiotherapy , Pinealoma/surgery , Pituitary Neoplasms/diagnostic imaging , Pituitary Neoplasms/radiotherapy , Pituitary Neoplasms/surgery , Stereotaxic Techniques , Tomography, X-Ray ComputedABSTRACT
From January 1986 to June 1989, the CT-guided stereotactic evacuation was performed in 38 cases of hypertensive intracerebral hematoma with satisfactory result. 24 patients were male and 14 female. The age ranged from 37 to 78 years, with an average of 55. 24 cases had their hematoma in internal capsule, 7 in cerebellum, 5 in subcortex, and 2 in brain stem. The interval between the occurrence of hemorrhage and evacuation of hematoma was 24 hours or less in 18 cases, 2-3 days in 14 and 4-7 days in 6. The volume of hematoma was estimated by CT scanning being more than 100 ml in 6 cases whereas much less in 2 cases of the brain stem.
Subject(s)
Cerebral Hemorrhage/surgery , Hematoma/surgery , Hypertension/complications , Stereotaxic Techniques , Adult , Aged , Female , Humans , Male , Middle Aged , Suction/methods , Tomography, X-Ray ComputedABSTRACT
30 patients with a hypertensive intracerebral hematoma were treated by stereotactic evacuation between 1986 and 1988. There were 20 males and 10 females; their ages ranged from 37 to 78 years. The time interval from onset to operation was in 16 patients 24 days and in 14 patients 2-7 days. In 19 patients the hematoma was found in the internal capsule, in 5 in the cerebellum, in 4 in the subcortex, and in 2 in the brain stem. The operation was performed with a Leksell computed tomography guided stereotactic apparatus and a Backlund hematoma evacuator. More than 80% of the hematoma could be aspirated in 20 patients and 60-80% in 10. 29 patients are alive, and 1 patient died.
