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1.
Epidemiol Health ; 45: e2023009, 2023.
Article in English | MEDLINE | ID: mdl-36596733

ABSTRACT

OBJECTIVES: Occupational stress management is particularly important for successful business operations, since occupational stress adversely affects workers' health, eventually lowering their productivity. Therefore, this study aimed to investigate the correlation between occupational stress and health-related productivity loss (HRPL) among Korean workers. METHODS: In 2021, 1,078 workers participated in a web-based questionnaire survey. HRPL was measured using the Work Productivity and Activity Impairment Questionnaire, and occupational stress was measured using the Korean Occupational Stress Scale-Short Form. The occupational stress level was divided into tertiles (low, intermediate, and high), and the low occupational stress group was used as the reference group. Using a generalised linear model, differences in labour productivity loss according to the level of occupational stress were tested after adjusting for demographic characteristics such as age, gender, education level, household income, occupation, and underlying medical conditions. RESULTS: Non-parametric regression analysis of HRPL according to occupational stress showed a direct association between occupational stress and HRPL. A statistically significant difference was observed in HRPL between participants with intermediate and high occupational stress and those with low occupational stress. CONCLUSIONS: Our results support the hypothesis that high occupational stress is associated with decreased labour productivity.


Subject(s)
Efficiency , Occupational Stress , Humans , Surveys and Questionnaires , Occupations , Republic of Korea
2.
Environ Sci Technol ; 47(19): 10964-70, 2013 Oct 01.
Article in English | MEDLINE | ID: mdl-24032692

ABSTRACT

Stronger regulations on nitrogen oxide (NOx) production have recently promoted the creation of a diverse array of technologies for NOx reduction, particularly within the combustion process, where reduction is least expensive. In this paper, we discuss a new combustion technology that can reduce NOx emissions within industrial burners to single-digit parts per million levels without employing exhaust gas recirculation or other NOx reduction mechanisms. This new technology uses a simple modification of commercial burners, such that they are able to perform plasma-assisted staged combustion without altering the outer configuration of the commercial reference burner. We embedded the first-stage combustor within the head of the commercial reference burner, where it operated as a reformer that could host a partial oxidation process, producing hydrogen-rich reformate or synthesis gas product. The resulting hydrogen-rich flow then ignited and stabilized the combustion flame apart from the burner rim. Ultimately, the enhanced mixing and removal of hot spots with a widened flame area acted as the main mechanisms of NOx reduction. Because this plasma burner acted as a low NOx burner and was able to reduce NOx by more than half compared to the commercial reference burner, this methodology offers important cost-effective possibilities for NOx reduction in industrial applications.


Subject(s)
Air Pollutants/analysis , Air Pollution/prevention & control , Nitrogen Oxides/analysis , Waste Management/methods , Air Pollutants/chemistry , Carbon Dioxide/chemistry , Carbon Monoxide/analysis , Carbon Monoxide/chemistry , Hot Temperature , Hydrogen/chemistry , Industrial Waste , Nitrogen Oxides/chemistry , Waste Management/instrumentation
3.
J Environ Radioact ; 97(1): 20-9, 2007.
Article in English | MEDLINE | ID: mdl-17418920

ABSTRACT

Lysimeter experiments were carried out in a greenhouse to study the fate of HTO following its soil deposition at different growth stages of Chinese cabbage. An HTO solution was applied to the surface of an acidic sandy soil at a time before, and four different times after, sowing. The transfer of HTO to the plants was quantified with the areal transfer factor (TFa, m2 kg(-1)-fresh) defined as the ratio of the plant concentration at harvest to the areal activity deposition. In the four post-sowing applications, the TFa values were in the ranges of 1.6 x 10(-5)-4.9 x 10(-3) for TFWT and 4.5 x 10(-6) -4.3 x 10(-5) for OBT, increasing with a decrease in the time interval between application and harvest. In the pre-sowing application, which was followed by a soil mixing, the TFa values for TFWT and OBT were 1.3 x 10(-4) and 8.6 x 10(-6), respectively. One week after harvest, soil samplings were made for the applications at 26 (A(26)) and 63d (A(63)) after sowing. Peaks of the depth profiles of the soil HTO appeared in the 10-15 cm layer for A(26) and the 5-10 cm layer for A(63). The top 30 cm of soil contained 0.5% and 20% of the applied activity for A(26) and A(63), respectively. Negligible fractions seemed to be in the deeper zone. It was estimated that almost all or most of the applied HTO had escaped to the air before plants' harvest.


Subject(s)
Brassica/drug effects , Environmental Exposure , Food Contamination, Radioactive , Soil Pollutants, Radioactive/toxicity , Biological Transport , Brassica/growth & development , Time Factors , Volatilization
4.
J Environ Radioact ; 92(1): 1-15, 2007.
Article in English | MEDLINE | ID: mdl-17081663

ABSTRACT

This paper describes the predictions of the transfer of 137Cs to rice plants following soil deposition during a non-growth season of rice by a dynamic compartment model considering the soil properties, and their comparison with experimental results. Major processes considered in the model were percolation, soil mixing by plowing, plant uptake, leaching to deep soil, fixation to clay mineral, and time-dependent growth of a plant. To consider the effects of the soil properties (pH, clay mineral, organic matter content, and exchangeable K) on plant uptake and the leaching rates of 137Cs in a root zone soil, the Absalom model was used for the present model. The 137Cs aggregated transfer factors (TFa, m2kg-1 dry plant) of rice plants for two consecutive cultivation years were obtained as a result of simulated 137Cs soil deposition experiments with 17 paddy soils of different properties, all of which were performed before transplanting of the rice. Observed 137Cs TFa values of the rice plants did not show an evident trend for the pH and clay content of the soil properties, while they increased with an increasing organic matter content and a decreasing exchangeable K concentration. Predicted 137Cs TFa values of the rice plants were found to be comparable with those observed.


Subject(s)
Cesium Radioisotopes/pharmacokinetics , Models, Biological , Oryza/metabolism , Soil Pollutants, Radioactive/pharmacokinetics , Soil , Ammonia/metabolism
5.
Health Phys ; 90(1): 42-55, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16340607

ABSTRACT

This paper describes a dynamic compartment model for evaluating the tritium level in agricultural plants after a short-term exposure to HTO vapor and its comparison with experimental results to test the predictive accuracy of the model. The model uses a time-dependent growth equation of a plant so that it can predict the contamination level of tritium depending on the stage of the growth of the plant, which is a major difference from some other compartment models using a constant crop yield. The model is able to calculate the time variable concentrations of the compartments representing the atmosphere, soil, and plants of four categories including leafy vegetables, root vegetables, grains, and tuber plants. Experimental results include the tissue free water tritium (TFWT) and the organically bound tritium (OBT) concentration of rice, soybean, cabbage, and radish exposed to HTO vapor for 1 h in the daytime at different growth stages. The model predictions showed that the model could simulate well not only the time-dependent tritium concentration of the plants but also the effect of the growth stage of the plant at the exposure time. Comparison of the model predictions with the experimental results suggested that the model could predict reasonably well the observed TFWT and OBT concentrations of the plants considered.


Subject(s)
Food Contamination, Radioactive , Plants, Edible/chemistry , Tritium/analysis , Agriculture , Volatilization , Water
6.
J Environ Radioact ; 76(3): 349-67, 2004.
Article in English | MEDLINE | ID: mdl-15261422

ABSTRACT

A dynamic compartment model has been studied to estimate the transfer of radionuclides deposited onto flooded rice-fields after an accidental release. In the model, a surface water compartment and a direct shoot-base absorption from the surface water to the rice-plant, which are major features discriminating the present model from the existing model, has been introduced to account for the flooded condition of rice-fields. The model has been applied to the deposition experiments of 137Cs on rice-fields that were performed at three different times to simulate the deposition before transplanting (May 2) and during the growth of the rice (June 1 and August 12), respectively. In the case of the deposition of May 2, the root-uptake is the most predominant process for transferring 137Cs to the rice-body and grain. When the radionuclide is applied just after transplanting (June 1), the activity of the body is controlled by the shoot-base absorption and the activity of the grain by the root-uptake. The deposition just before ear-emergence (August 12) shows that the shoot-base absorption contributes entirely to the increase of both the activities of the body and grain. The model prediction agrees within one or two factors with the experimental results obtained for a respective deposition experiment.


Subject(s)
Food Contamination , Models, Theoretical , Radioactive Hazard Release , Water Pollutants, Radioactive/analysis , Water Pollutants, Radioactive/pharmacokinetics , Cesium Radioisotopes/analysis , Disasters , Forecasting , Oryza , Plant Roots , Risk Assessment
7.
Cancer Res ; 62(21): 6318-22, 2002 Nov 01.
Article in English | MEDLINE | ID: mdl-12414663

ABSTRACT

Glioblastoma is a severe type of primary brain tumor and its invasion is strongly correlated with the secretion of matrix metalloproteinases (MMPs). To investigate a role of PTEN, a tumor suppressor gene, in the regulation of hyaluronic acid (HA)-induced invasion of glioma cells, we examined the secretion of MMP-9 in various glioma cells with or without a functional PTEN gene. The secretion of MMP-9 in glioma cells lacking functional PTEN (U87MG, U251MG, and U373MG) was induced by HA, although not in wildtype (wt)-PTEN-harboring cells (LN229, LN18, and LN428). In addition, stable expression of wt-PTEN into U87MG cells significantly decreased the secretion of HA-induced MMP-9 and basal levels of MMP-2, inhibiting the activation of focal adhesion kinase and extracellular signal-regulated kinase 1/2, whereas the secretion levels of the tissue inhibitor of metalloproteinase-1 and -2 were increased, finally resulting in the inhibition of invasion by HA in vitro. Ectopic expressions of adenoviral (Ad)-wt-PTEN and -lipid phosphatase-deficient (G129E)-PTEN, but not both protein and -lipid phosphatase-deficient (C124S)-PTEN, reduced MMP-9 secretion and invasion by HA. These results were also confirmed by expressions of Ad-wt-PTEN and Ad-G129E-PTEN in other glioblastoma cells lacking functional PTEN, U251MG, and U373MG. These findings strongly suggest the possibility that PTEN may block HA-induced MMP-9 secretion and invasion through its protein phosphatase activity.


Subject(s)
Glioblastoma/enzymology , Hyaluronic Acid/antagonists & inhibitors , Matrix Metalloproteinase 9/biosynthesis , Phosphoric Monoester Hydrolases/physiology , Protein-Tyrosine Kinases/metabolism , Tumor Suppressor Proteins/physiology , Focal Adhesion Kinase 1 , Focal Adhesion Protein-Tyrosine Kinases , Glioblastoma/metabolism , Glioblastoma/pathology , Humans , Hyaluronic Acid/pharmacology , Matrix Metalloproteinase 9/metabolism , Mitogen-Activated Protein Kinase 1/metabolism , Mitogen-Activated Protein Kinase 1/physiology , Mitogen-Activated Protein Kinase 3 , Mitogen-Activated Protein Kinases/metabolism , Mitogen-Activated Protein Kinases/physiology , Neoplasm Invasiveness , PTEN Phosphohydrolase , Phosphoprotein Phosphatases/metabolism , Phosphoric Monoester Hydrolases/genetics , Phosphoric Monoester Hydrolases/metabolism , Phosphorylation/drug effects , Protein-Tyrosine Kinases/physiology , Signal Transduction/drug effects , Signal Transduction/physiology , Transfection , Tumor Cells, Cultured , Tumor Suppressor Proteins/genetics , Tumor Suppressor Proteins/metabolism , ras Proteins/metabolism , ras Proteins/physiology
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