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1.
Zhonghua Yan Ke Za Zhi ; 60(5): 451-453, 2024 May 11.
Article in Chinese | MEDLINE | ID: mdl-38706084

ABSTRACT

A 36-year-old male patient presented with a decrease in vision after undergoing scleral suturing for a left eye injury caused by an iron hook, combined with intravitreal injection of cefuroxime. Ocular examination revealed extensive gray-white edematous areas in the macular region, along with focal serous shallow retinal detachment in the posterior pole. Following admission, comprehensive ophthalmic examinations were conducted, leading to the diagnosis of toxic retinal damage in the left eye. Treatment with oral corticosteroids and interventions to improve microcirculation were initiated, resulting in improved visual acuity. At the six-month follow-up, the patient's visual acuity had recovered to 0.5.


Subject(s)
Cefuroxime , Humans , Male , Adult , Cefuroxime/adverse effects , Cefuroxime/administration & dosage , Intravitreal Injections , Anti-Bacterial Agents/adverse effects , Retinal Detachment , Retina
2.
Nanotechnology ; 31(9): 095502, 2020 Feb 21.
Article in English | MEDLINE | ID: mdl-31675732

ABSTRACT

Flexible photodetector shows great potential applications in intelligent wearable devices, health monitoring, and biological sensing. In this work, single crystal ß-tellurium nanowires were grown on flexible muscovite by molecular beam epitaxy, constructing high-density ordered nanomesh structure. The prepared photodetectors based on tellurium nanomesh exhibit excellent mechanical flexibility, fast response in a broad range from ultraviolet to near-infrared, and good photosensitivity. We found that the flexible photodetectors with Shottky contact drastically suppressed dark current, while the response speed was lowered in comparison to the devices with ohmic contact, as holes would take a long time to tunnel through the Shottky barrier between metal and p-type Te. Moreover, the photoresponse of flexible Shottky photodetectors can be modulated by piezoelectricity of tellurium, and pronounced photocurrent increase after bending many times. Under external stress, polarization charges could tune Shottky barrier height of the metal/tellurium, resulting in variation of photocurrent. This research not only explores the broadband photoresponse and piezoelectric effect of tellurium nanomesh, but also promotes the integration and development of broadband flexible optoelectronic devices.

3.
Acta Neurochir (Wien) ; 142(11): 1263-73; discussion 1273-4, 2000.
Article in English | MEDLINE | ID: mdl-11201642

ABSTRACT

A co-operative study was conducted to determine the clinical characteristics of patients with moyamoya disease who were diagnosed and treated at neurosurgical institutes in Korea before 1995. Twenty-six hospitals contributed 505 cases and among them, the clinical characteristics of 334 patients with definite moyamoya disease were evaluated. The number of patients began to increase from the late 1980s, and after that approximately 20 patients were treated each year. There were two age peaks: from six to 15 and from 31 to 40 years of age. Haemorrhagic manifestations occurred in approximately 43% of the patients. The major clinical manifestations were haemorrhage in adults (62.4%) and ischaemia in children (61.2%). Overall 54.5% of the patients experienced decreased consciousness levels, mainly due to intracranial haemorrhage or cerebral infarction. In the patients with ischemic manifestations, the adult patients were more likely to have cerebral infarction than the pediatric patients (80% vs. 39%) and the pediatric patients were more likely to have TIA (61% vs. 25%). Thirty eight percent of the patients underwent bypass surgery and 53% of these procedures were performed bilaterally. Treatment policies, including indications for bypass surgery and commonly used drugs, were somewhat different according to the institution. Overall favorable outcome was 73%, and the most significant factor affecting poor outcome was haemorrhagic manifestation. This article describes the characteristics of 334 patients with moyamoya disease, who were diagnosed and treated at neurosurgical institutes in Korea before 1995.


Subject(s)
Cerebral Revascularization/methods , Moyamoya Disease/pathology , Adolescent , Adult , Age of Onset , Aged , Brain Ischemia/etiology , Cerebral Infarction/etiology , Child , Child, Preschool , Female , Humans , Incidence , Infant , Intracranial Hemorrhages/etiology , Korea/epidemiology , Male , Middle Aged , Moyamoya Disease/epidemiology , Moyamoya Disease/surgery , Prognosis , Retrospective Studies
5.
J Nutr Sci Vitaminol (Tokyo) ; 43(3): 345-55, 1997 Jun.
Article in English | MEDLINE | ID: mdl-9268922

ABSTRACT

To evaluate the antioxidant effects of beta-carotene and astaxanthin, rat liver microsomes were exposed to a mixture of chelated iron (Fe3+/ADP) and NADPH. The carotenoids (190 pmol/mg protein) were incorporated into some of these microsomal membranes, and phospholipid hydroperoxides (PLOOH), thiobarbituric acid reactive substances (TBARS) and endogenous alpha-tocopherol content were measured over time after the initiation of oxidant stress. In control microsomes, oxidant stress led to accumulation of 1,865 (+/- 371) pmol PLOOH/mg protein during the initial 10-min peroxidation reaction, followed by a more gradual decrease during the subsequent 20-min of reaction. PLOOH accumulation during the initial 10-min reaction period was reduced to 588 (+/- 169) pmol/mg protein with beta-carotene present and 800 (+/- 288) pmol/mg protein with astaxanthin present. During the following 20-min of incubation, PLOOH levels declined in the carotenoid-supplemented microsomes but continued to increase at a slower rate in control preparations. TBARS did not show such large accumulation as observed in PLOOH during the initial 10-min incubation in any microsomal sample. The presence of carotenoids in the microsomal membrane partially inhibited the loss of alpha-tocopherol, especially during the later phase of oxidant stress. When lipid peroxidation is generated by membrane-bound cyt-P450, the specific measurement of PLOOH clearly demonstrates that the presence of carotenoids provides antioxidant protection.


Subject(s)
Lipid Peroxidation/drug effects , Microsomes, Liver/drug effects , NADP/metabolism , Phospholipids/metabolism , beta Carotene/analogs & derivatives , beta Carotene/pharmacology , Animals , Lipid Peroxides/metabolism , Male , Microsomes, Liver/metabolism , Rats , Rats, Sprague-Dawley , Thiobarbituric Acid Reactive Substances/metabolism , Vitamin E/metabolism , Xanthophylls
6.
Asian Pac Migr J ; 5(2-3): 265-79, 1996.
Article in English | MEDLINE | ID: mdl-12320772

ABSTRACT

"After presenting the three major types of migrant workers currently in South Korea--professional employees, technical trainees and illegal workers--this article examines the role of contractors and other middle-men to expose the possibility of ¿intermediary exploitation'. The results of such exploitation are illustrated in the living and working conditions of foreign workers."


Subject(s)
Employment , Health Workforce , Human Rights , Personnel Selection , Quality of Life , Transients and Migrants , Asia , Demography , Developing Countries , Economics , Emigration and Immigration , Asia, Eastern , Health Planning , Korea , Organization and Administration , Population , Population Dynamics , Social Class , Social Welfare , Socioeconomic Factors
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