ABSTRACT
The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing.
Subject(s)
Bandages , Biocompatible Materials/chemistry , Carboxymethylcellulose Sodium/chemistry , Nanoparticles/chemistry , Polymers/chemistry , Wound Healing , Animals , Cellulose , Humans , Hydrogels/chemistry , Infection Control , Mice , Printing, Three-Dimensional , UlcerABSTRACT
Alginate biopolymer has been used in the design and development of several wound dressing materials in order to improve the efficiency of wound healing. Mainly, alginate improves the hydrophilic nature of wound dressing materials in order to create the required moist wound environment, remove wound exudate and increase the speed of skin recovery of the wound. In addition, alginate can easily cross-link with other organic and inorganic materials and they can promote wound healing in clinical applications. This review article addresses the importance of alginates and the roles of derivative polymeric materials in wound dressing biomaterials. Additionally, studies on recent alginate-based wound dressing materials are discussed.
Subject(s)
Alginates/chemistry , Biocompatible Materials/chemistry , Bandages, Hydrocolloid , Humans , Hydrogels/chemistry , Nanoparticles/chemistry , Polymers/chemistryABSTRACT
A few fruits have short post-harvest life due to high metabolic activity, relatively high water content vulnerability towards microbes and loss of weight during their storage. Carboxymethyl cellulose (CMC)-Guar gum-silver nanocomposite films (CG-Ag0NC) are developed to address these issues. The silver nanoparticles were generated in the CMC-Guar gum matrix through a reduction by Mentha leaves extract. All the films were characterized by UV-vis spectroscopy, FT-IR, TGA, XRD, SEM, TEM, and zeta potential measurements. The antimicrobial activity of CG and CG-Ag0NC was measured by determining their zone inhibition values with ten food pathogenic microbes. The shelf life of CG-Ag0NC films was tested with the model fruit, strawberries, and compared with other packing films. The results are encouraging in terms of freshness, shelf-life and weight loss.
