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Eksp Klin Farmakol ; 63(6): 28-9, 2000.
Article in Russian | MEDLINE | ID: mdl-11202506

ABSTRACT

Verapamil and gynipral administered to pregnant rats in doses on a clinical level suppress the uterine contractions, which is manifested by a decrease in the amplitude and frequency of the biopotential. The joint administration of gynipral and verapamil (in half doses) resulted in a pronounced tocolytic effect.


Subject(s)
Adrenergic beta-Agonists/pharmacology , Calcium Channel Blockers/pharmacology , Hexoprenaline/pharmacology , Tocolytic Agents/pharmacology , Uterine Contraction/drug effects , Verapamil/pharmacology , Animals , Drug Synergism , Female , Myometrium/physiology , Pregnancy , Rats , Rats, Wistar
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