ORCA: A picture database of object-scene arrangements for cross-cultural and aging research.

In recent years, cross-cultural research on the modulation of basic cognitive processes by culture has intensified - also from an aging perspective. Despite this increased research interest, only a few cross-culturally normed non-verbal stimulus sets are available to support cross-cultural cognitive research in younger and older adults. Here we present the ORCA (Official Rating of Complex Arrangements) picture database, which includes a total of 720 object-scene compositions sorted into 180 quadruples (e.g., two different helmets placed in two different deserts). Each quadruple contains visually and semantically matched pairs of objects and pairs of scenes with varying degrees of semantic fit between objects and scenes. A total of 95 younger and older German and Chinese adults rated every object-scene pair on object familiarity and semantic fit between object and scene. While the ratings were significantly correlated between cultures and age groups, small but significant culture and age differences emerged. Object familiarity was higher for older adults than younger adults and for German participants than for Chinese participants. Semantic fit was rated lower by German older adults and Chinese younger adults as compared to German younger adults and Chinese older adults. Due to the large number of stimuli, our database is particularly well suited for cognitive and neuroscientific research on cross-cultural and age-related differences in perception, attention, and memory.

Developmental differences in processing the valence and magnitude of incentive cues: Mid-adolescents are more sensitive to potential gains than early- or late-adolescents.

Recent research has focused on the interaction between motivation and cognitive control and shown that both are important for goal-directed behavior. There also is evidence for developmental differences in the sensitivity and behavioral effectiveness of incentives, showing that mid-adolescents might be especially susceptible to rewards. Further pursuing this line of research, the present study examined developmental differences in incentive processing and whether these potential differences also would correspond to changes in cognitive control. We compared the processing of high and low potential gains and losses in early-, mid-, and late adolescents by means of event-related potentials (ERPs) and examined whether these incentives also led to specific performance differences in task-switching. We expected that potential gains compared to potential losses and high compared to low incentives would lead to more preparatory updating as reflected in the P3b and consequently to better task performance and smaller global and local switch costs as indicators of cognitive control in all age groups. Furthermore, we expected that mid-adolescents should be especially sensitive to high gains and thus show the most pronounced enhancements in task performance and global and local switch costs in trials with high gains, respectively. Our results corroborate the idea of a special sensitivity to high rewards during mid-adolescence. The analysis of ERPs showed age-related differences in the processing of incentive cues that also varied with cognitive control demands. However, the different incentives did not impact age-related differences in indices of cognitive control, but had a general effect on response speed.

Neurofeedback Treatment of Negative Symptoms in Schizophrenia: Two Case Reports.

Negative symptoms of schizophrenia, like diminished emotional expression and a dearth of self-initiated behavior do not respond reliably to anti-psychotic medication or to conventional psychotherapeutic approaches. Starting from evidence on the probable neural basis of such symptoms and on the effectiveness of neurofeedback with other psychological disorders, the present case study applied 20 sessions of EEG neurofeedback to a 45-year-old female and a 30-year-old male, both diagnosed with severe negative symptoms of schizophrenia. In both cases GAF scores were improved significantly and at the end of treatment, both patients did not meet the diagnostic criteria of negative symptomatology any longer. Symptom reduction went along with an obvious improvement of social, interpersonal, and cognitive abilities according to the clinical impression. Detailed data analysis revealed that these improvements went along with corresponding changes of EEG parameters and with distinct patterns and strategies of change in each of the two individuals. The results suggest that EEG neurofeedback should be examined on a larger scale as it offers a promising alternative to existing treatment approaches for negative symptoms in schizophrenia.