ABSTRACT
Anaerobiospirillum succiniciproducens is a rare anaerobic pathogen that is implicated in sporadic cases of bacteremia and diarrhea, usually in immunocompromised patients. We describe a case of prosthetic joint infection in a 71 year old male who presented with right hip pain. Anaerobic cultures from tissue specimen grew a spiral-shaped gram-negative rod, identified as A. succiniciproducens by 16S rRNA gene sequencing. The patient was treated successfully with IV cefoxitin for 6 weeks. To our knowledge this is only the third reported case of prosthetic joint infection due to A. succiniciproducens.
Subject(s)
Anaerobiospirillum , Arthritis, Infectious , Bacteremia , Gram-Negative Bacterial Infections , Male , Humans , Aged , RNA, Ribosomal, 16S/genetics , Gram-Negative Bacterial Infections/diagnosis , Gram-Negative Bacterial Infections/drug therapy , Anaerobiospirillum/geneticsABSTRACT
Clostridium difficile infection is one of the most common causes of healthcare-associated morbidity and mortality. ExtraintestinalC. difficile infection is extremely rare; though a variety of infections involving different organs have been reported. We report the first case of scrotal abscess due toC. difficile in an 84 year old male following left inguinal herniorrhaphy. Patient underwent surgical drainage of scrotal abscess and was successfully treated with culture directed antibiotic therapy.
Subject(s)
Abscess/diagnosis , Abscess/microbiology , Clostridioides difficile , Clostridium Infections/diagnosis , Clostridium Infections/microbiology , Scrotum/microbiology , Scrotum/pathology , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Biomarkers , Clostridium Infections/drug therapy , Humans , Male , Symptom Assessment , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
Gastric antral vascular ectasia is the source of up to 4% of nonvariceal upper gastrointestinal bleeding. It can present with occult bleeding requiring transfusions or with acute gastrointestinal bleeding. It is associated with significant morbidity and mortality and has been associated with such underlying chronic diseases as scleroderma, diabetes mellitus, and hypertension. Approximately 30% of cases are associated with cirrhosis. We report two cases of gastric antral vascular ectasia with two strikingly different endoscopic appearances. We further describe the clinical, endoscopic, histologic, and therapeutic aspects of this entity.
