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1.
Medicine (Baltimore) ; 103(16): e37867, 2024 Apr 19.
Article in English | MEDLINE | ID: mdl-38640327

ABSTRACT

Quality of recovery (QoR) is a significant component of peri-operative health status and is influenced by patients' characteristics and surgical and anesthetic methods. The QoR-15 scale is a patient-reported outcome questionnaire that measures postoperative QoR. The validity of the QoR-15 scale has been proven in many languages. In this study, we aimed to translate the QoR-15 questionnaire into Turkish and evaluate its validity in the Turkish population. After being translated into Turkish, the questionnaire was administered to 190 patients who underwent obstetric, gynecological, orthopedic, or thoracic surgery under general or regional anesthesia. The Turkish version of QoR-15 (QoR-15T) was administered 2 times: before surgery and 24 hour after surgery. The feasibility, reliability, validity and responsiveness of the QoR-15T were evaluated. Because 13 patients were discharged within 24 hour postoperatively, the study was completed with 177 patients. The recruitment and completion rates of questionnaire were 95% and 93.1% respectively. The completing time of the questionnaire was 2.5 minutes preoperatively and 3.5 minutes postoperatively. The scale yielded a Cronbach α value of 0.75, a Cohen effect size of 1.42, and a standardized response mean of 1.39. There was a significant positive correlation (95% confidence interval; R = 0.68, P < .001) between QoR-15T and visual analog scale postoperatively. The correlation of the items with the total QoR-15T score ranged from 0.19 to 0.60. The total scores of preoperative and postoperative QoR-15T were mean: 130.67, standard deviation: 15.78 and mean: 108.23, standard deviation: 13.06, respectively, with a significant difference between them (P < .01). The QoR-15T is feasible, reliable, valid, and responsive among patients undergoing surgery under general and regional anesthesia.


Subject(s)
Anesthesia Recovery Period , Quality of Life , Humans , Reproducibility of Results , Health Status , Surveys and Questionnaires
2.
Agri ; 35(2): 76-82, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37052163

ABSTRACT

OBJECTIVES: Inguinal hernia repair is one of the most common daily surgeries performed in pediatrics. This prospective randomized clinical trial aims to compare ultrasound (USG)-guided ilioinguinal/iliohypogastric (IL/IH) nerve block and pre-incisional wound infiltration (PWI) in terms of post-operative analgesia on pediatric unilateral inguinal hernia repair. METHODS: After receiving ethics committee approval, 65 children aged 1-6 years who had unilateral inguinal hernia repair were allocated to USG-guided IL/IH nerve block (group IL/IH, n=32) and (group PWI, n=33). In both groups, 0.5 mg/kg 0.25% bupivacaine+2% prilocaine mixture was used by calculating the volume as 0.5 mL/kg for the block and infiltration. The primary outcome was to compare both groups' post-operative Face, Legs, Activity, Cry and Consolability (FLACC) scores. The secondary outcomes included the time to first analgesic request and the total acetaminophen consumption. RESULTS: The FLACC pain scores at the 1st, 3rd, 6th, and 12th h were statistically significantly lower in group IL/IH than in group PWI (p=0.013, p<0.001, p<0.001, and p=0.037, respectively) (p<0.001). There was no difference between the groups at the 10th and 30th min and at 24 h (p=0.472, p=0.586, and p=0.419, respectively) (p>0.05). CONCLUSION: USG-guided IL/IH nerve block in pediatric patients with inguinal hernia repair was found to be superior to PWI in terms of lower pain scores, less additional analgesia requirement, and longer first analgesia requirement.


Subject(s)
Hernia, Inguinal , Nerve Block , Humans , Child , Hernia, Inguinal/surgery , Pain, Postoperative/prevention & control , Prospective Studies , Ultrasonography, Interventional
3.
Indian Pediatr ; 60(1): 108-112, 2023 02 15.
Article in English | MEDLINE | ID: mdl-36604940

ABSTRACT

BACKGROUND: Obesity has become a serious problem not only in adult patients but also in pediatric patients. AIM: To evaluate whether obesity affects the recovery profile after general anesthesia in children. PARTICIPANTS: 40 children (aged 2-12 years) who underwent surgery under general anesthesia and had an American Society of Anesthesiologists (ASA) physical I and II. METHODS: This prospective cohort study was conducted over a period of 3 months (January- April, 2021). The patients were divided into two groups according to body mass index (BMI): Group I comprised obese children (BMI ≥95th for age percentile) (n=20) and Group II comprised children with a normal BMI (25-75th for-age percentile) (n=20). Anesthesia induction and maintenance were performed as per standard guidelines in both the groups. OUTCOME: The recovery profile was evaluated with the following parameters: time to spontaneous ventilation, laryngeal mask airway removal time, time to open eyes, and post-anesthesia care unit discharge time. RESULTS: When the recovery profiles were compared, no significant differences were found between the groups. Time to spontaneous ventilation [mean difference (95% CI); 0.66 (0.09-1.42); P=0.085], laryngeal mask airway removal time [MD (95% CI); 1.12 (0.06-2.22); P=0.057), time to open eyes [MD (95% CI) 0.66 (0.40-1.74); P=0.217], and post-anesthesia care unit dis-charge time [MD (95% CI) 3.60 (0.59-7.25); P=0.054] were higher in Group II; however, these differences lacked both statistical and clinical significance. CONCLUSION: The results suggest that obesity has no effect on the recovery profile after general anesthesia in children in our setting.


Subject(s)
Laryngeal Masks , Pediatric Obesity , Adult , Humans , Child , Prospective Studies , Pediatric Obesity/epidemiology , Anesthesia, General/adverse effects , Anesthesia, General/methods , Time Factors
4.
J Clin Med ; 13(1)2023 Dec 23.
Article in English | MEDLINE | ID: mdl-38202092

ABSTRACT

Early diagnosis and treatment of postspinal hypotension (PSH) in obstetric anaesthesia reduces the risk of maternofetal complications. In this study, the effect of EtCO2 and the integrated pulmonary index (IPI) in predicting PSH was investigated. Patients scheduled for cesarean section under spinal anaesthesia were included. The Capnostream 35 respiratory monitor (Medtronic, Inc., Dublin, Ireland) was used for EtCO2 and IPI. PSH developed in 52 (63.4%) of the 82 patients. EtCO2 and IPI values decreased significantly compared with baseline values in patients who developed PSH. There were statistically significant differences in EtCO2 (p = 0.001) and the IPI change (p = 0.045) in patients who developed PSH compared with those who did not. It was found that the EtCO2 difference had an independent effect on predicting PSH (p < 0.05), whereas the IPI difference did not (p > 0.05). One unit decrease in EtCO2 from the baseline increased the risk of PSH by 3.3 times. ROC curve analysis showed that the magnitude of change in EtCO2 was diagnostic for predicting PSH (AUC: 0.90 (0.83-0.97; p < 0.001)). IPI showed no predictive value for postspinal hypotension in cesarean section. However, EtCO2 monitoring, which is non-invasive and real-time monitoring, can be used to predict postspinal hypotension.

5.
Turk J Med Sci ; 52(5): 1627-1638, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36422504

ABSTRACT

BACKGROUND: Morphological differences that can lead the trigeminal nerve to neurovascular conflict and a new solitary pontine lesion are associated with the pathogenesis of trigeminal neuralgia (TN). In this case-control study, we aimed to contribute to the current discussions about the pathogenesis of TN by investigating the anatomical structures that may have an effect on the morphometric parameters of the trigeminal nerve. METHODS: This study included 25 patients with TN followed up for pain in the Department of Algology, Faculty of Medicine, and 25 age- and gender-matched controls. We performed morphometric measurements including the length and volume of the trigeminal nerve, cerebellopontine cistern, pons, and posterior fossa in the MRIs of these individuals. Comparative analyses were performed for the mean of the affected and unaffected sides of the TN patients and the right, left, and both sides of the control group. RESULTS: In patients with TN, on the affected side, length and volume of the trigeminal nerve and cerebellopontine cistern volume were found smaller than controls (p < 0.05). Pons volume was higher in patients with TN compared to controls (p < 0.05). The length of the affected nerve was significantly related to prepontine cistern length and cerebellopontine cistern volume (p < 0.05). DISCUSSION: The cerebellopontine cistern volume has a significant impact on the morphometric characteristics of the trigeminal nerve. Especially, whether the increase in the volume of pons causes a decrease in the volume of cerebellopontine cistern should be clarified with further research.


Subject(s)
Trigeminal Neuralgia , Humans , Trigeminal Neuralgia/diagnostic imaging , Trigeminal Neuralgia/etiology , Case-Control Studies , Trigeminal Nerve/diagnostic imaging , Pons/diagnostic imaging , Pons/pathology , Magnetic Resonance Imaging
6.
Turk J Med Sci ; 52(4): 997-1005, 2022 Aug.
Article in English | MEDLINE | ID: mdl-36326371

ABSTRACT

BACKGROUND: This study was designed to observe and compare the performance of fiberoptic laryngeal (FOL) view, leakage test (LT) and ultrasonography (USG) usage in detecting i-gel position in pediatric patients. METHODS: One hundred ten consecutive children were included in this single-armed prospective observational study. After anesthetic induction, i-gel placement confirmed using FOL and LT was evaluated using USG in three planes. According to our scoring system, acceptable and unacceptable grades (FOL, LT and USG) were determined to describe placement. Sensitivity and specificity were determined by comparing USG performance with the other two tests. RESULTS: Ultrasonography was found a sensitivity of 20% positive predictive value (PPV) for unacceptable i-gel placement according to FOL grade and a sensitivity of 37.04% with a 100% PPV according to LT grade. USG was found a specificity of 91.84% negative predictive value (NPV) of 91.84% for acceptable i-gel placement according to FOL grade and the NPV specificity of 100% with a 82.65% NPV according to LT grade. DISCUSSION: Ultrasonography demonstrated a very good diagnostic performance in the detection of optimal i-gel placement according to both FOL and LT. However, both FOL and LT showed poor diagnostic performance compared to USG in demonstrating i-gel malposition.


Subject(s)
Ultrasonography , Humans , Child , Sensitivity and Specificity , Prospective Studies , Predictive Value of Tests
7.
Sisli Etfal Hastan Tip Bul ; 56(3): 386-390, 2022.
Article in English | MEDLINE | ID: mdl-36304226

ABSTRACT

Objectives: Although ganglion impar blockade has long been an effective procedure in the treatment of coccydynia, the pulsed radiofrequency (PRF) of the ganglion impar (GI) is a relatively new approach for the management of coccydynia. In the present study, we aimed to retrospectively evaluate patients who underwent GI PRF due to coccydynia. Methods: Twenty-six patients diagnosed with coccydynia and treated with a PRF of the GI were included in this retrospective study. Clinical characteristics of the patients and treatment success were evaluated. Pain intensity was evaluated using a visual analog scale (VAS). Results: The study included 19 (73.1%) female and 7 (26.9%) male patients. The median age of the patients was 45 (IQR: 24-60) years, and the etiology of pain was trauma in 21 (80.8%) of the 26 patients evaluated. There was a statistically significant decrease in VAS scores after GI PRF (Respectively; 6 [IQR: 6-7] and 2 [IQR: 0-3]). The PRF of the GI treatment success was 84.6%. Treatment success was 100% in patients with neuropathic pain and 59.1% in patients with nociceptive pain. Conclusion: GI PRF is an effective and reliable procedure with low complication rate for pain relief in coccydynia.

8.
J Invest Surg ; 34(2): 157-163, 2021 Feb.
Article in English | MEDLINE | ID: mdl-31116047

ABSTRACT

Background: Lumbar puncture's (LP) success is dependent on the skill of the physician, anatomy, size, and posture of the patient. Aims: The purpose of this study was to describe a method that could be used to help estimate the correct depth of needle (Y) insertion in children based on age, weight (W), and height (H). Methods: The study consisted of 200 children American Society of Anesthesiologist class I-II aged 0-12 years who underwent spinal block for orthopedic, pediatric, and genitourinary surgery. The distance from the skin entry point to the tip of the spinal needle was measured after the LP was performed. The relationship between the Y and W, H and body mass index (BMI) was calculated. Predictive statistical models were used to determine the LP needle depth. A paired sample t-test was conducted to compare the findings of the developed model with those of earlier models. Results: The patients were aged 2-144 months, with H and W of 43-154 cm and 2.5-48 kg, respectively. The BMI was 10.75-37.72 kg/m2. Before the Y was estimated, the relationship between the independent variables and the depth variable, which was the dependent variable, was examined. According to the obtained results, the model consists of strong relationships with H, W, and H + W. The formula for predicting Y based on W plus H was as follows: for all patients: Y (cm) = 0.861 + 0.012 × H (cm) + 0.035 × W (kg). Based on H, the formula for predicting the required Y was as follows: For all patients: Y (cm) = 0.393 + 0.023 × H (cm). Based on W, the formula for predicting the required Y was as follows: For all patients: Y (cm) = 1.460 + [0.067 × W (kg)]. Conclusion: The formula may provide a more reliable estimate of the required LP depth in children than that obtained using current models. However, larger studies are needed to standardize the formula.


Subject(s)
Anesthesia, Spinal , Spinal Puncture , Body Mass Index , Child , Humans , Needles , Skin , Spinal Puncture/adverse effects
9.
Sao Paulo Med J ; 137(1): 45-53, 2019 May 08.
Article in English | MEDLINE | ID: mdl-31116270

ABSTRACT

BACKGROUND: Both postoperative pain control and range of motion are important in total knee arthroplasty (TKA). However, in the literature, there is little comparison of peripheral nerve blocks and periarticular infiltration techniques using levobupivacaine. The aim of our study was to measure pain with visual analogue scale (VAS) and knee range of motion (ROM) between in patients undergoing adductor canal block (ACB) for TKA using levobupivacaine compared to periarticular levobupivacaine infiltration (PAI-L). DESIGN AND SETTING: Prospective randomized clinical trial in a university hospital. METHODS: Patients aged 40-85 years who underwent unilateral TKA were included; 39 were treated withperiarticular infiltration using 40 ml (0.125 mg) of levobupivacaine (PAI-L group); and 40 were treated with ACB using 20 ml of 0.25% levobupivacaine (ACB-L group). Postoperative pain scores at rest and during active physical therapy were assessed using a VAS, along with knee ROM in flexion and extension. In addition, 100-foot walking time results, total morphine consumption and time of first analgesia requirement were recorded postoperatively. RESULTS: VAS scores at rest and during active physical therapy and the total amount of morphine consumed were lower in the ACB-L group than in the PAI-L group (P < 0.05). In contrast, knee ROM in flexion and extension and 100-foot walking times were greater in the PAI-L group than in the ACB-L group (P < 0.05). CONCLUSION: ACB-L was superior to PAI-L regarding pain treatment after TKA; however, PAI-L was superior to ACB-L regarding postoperative ROM and walking ability. CLINICAL TRIAL REGISTRY: ACTRN-12618000438257.


Subject(s)
Anesthetics, Local/administration & dosage , Arthroplasty, Replacement, Knee/adverse effects , Levobupivacaine/administration & dosage , Muscle, Skeletal/drug effects , Nerve Block/methods , Pain, Postoperative/prevention & control , Ultrasonography, Interventional/methods , Adult , Aged , Aged, 80 and over , Arthroplasty, Replacement, Knee/methods , Female , Humans , Injections, Intramuscular , Male , Middle Aged , Pain Measurement , Postoperative Period , Prospective Studies , Range of Motion, Articular/drug effects , Range of Motion, Articular/physiology , Reference Values , Reproducibility of Results , Time Factors , Treatment Outcome , Walk Test/methods
10.
São Paulo med. j ; 137(1): 45-53, Jan.-Feb. 2019. tab, graf
Article in English | LILACS | ID: biblio-1004748

ABSTRACT

ABSTRACT BACKGROUND: Both postoperative pain control and range of motion are important in total knee arthroplasty (TKA). However, in the literature, there is little comparison of peripheral nerve blocks and periarticular infiltration techniques using levobupivacaine. The aim of our study was to measure pain with visual analogue scale (VAS) and knee range of motion (ROM) between in patients undergoing adductor canal block (ACB) for TKA using levobupivacaine compared to periarticular levobupivacaine infiltration (PAI-L). DESIGN AND SETTING: Prospective randomized clinical trial in a university hospital. METHODS: Patients aged 40-85 years who underwent unilateral TKA were included; 39 were treated withperiarticular infiltration using 40 ml (0.125 mg) of levobupivacaine (PAI-L group); and 40 were treated with ACB using 20 ml of 0.25% levobupivacaine (ACB-L group). Postoperative pain scores at rest and during active physical therapy were assessed using a VAS, along with knee ROM in flexion and extension. In addition, 100-foot walking time results, total morphine consumption and time of first analgesia requirement were recorded postoperatively. RESULTS: VAS scores at rest and during active physical therapy and the total amount of morphine consumed were lower in the ACB-L group than in the PAI-L group (P < 0.05). In contrast, knee ROM in flexion and extension and 100-foot walking times were greater in the PAI-L group than in the ACB-L group (P < 0.05). CONCLUSION: ACB-L was superior to PAI-L regarding pain treatment after TKA; however, PAI-L was superior to ACB-L regarding postoperative ROM and walking ability. CLINICAL TRIAL REGISTRY: ACTRN-12618000438257.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Pain, Postoperative/prevention & control , Muscle, Skeletal/drug effects , Arthroplasty, Replacement, Knee/adverse effects , Levobupivacaine/administration & dosage , Anesthetics, Local/administration & dosage , Nerve Block/methods , Postoperative Period , Reference Values , Time Factors , Pain Measurement , Prospective Studies , Reproducibility of Results , Range of Motion, Articular/drug effects , Range of Motion, Articular/physiology , Treatment Outcome , Ultrasonography, Interventional/methods , Arthroplasty, Replacement, Knee/methods , Walk Test/methods , Injections, Intramuscular
11.
Turk Neurosurg ; 29(2): 285-288, 2019.
Article in English | MEDLINE | ID: mdl-30649827

ABSTRACT

AIM: To assess reliability by comparing the Full Outline of Unresponsiveness (FOUR) scores and Glasgow Coma Scale (GCS) values assigned by specialists from two different fields to patients in the Anesthesiology and Reanimation and Neurosurgery intensive care units. MATERIAL AND METHODS: This study was conducted between March 2017 and June 2017 at Selcuk University Faculty of Medicine, Departments of Anesthesiology and Reanimation and Neurosurgery. Seventy-nine patients aged 18-65 years who were treated for at least 24 hours in the intensive care unit were independently assessed by two raters, an anesthesiologist and a neurosurgeon,using FOUR and GCS. The Kolmogorov-Smirnov normality test was applied for continuous variables, and SPSS 20.0 version software was used for data analyses. RESULTS: There were no significant differences between FOUR scores and GCS values given by the two raters. The mortality rate among patients with low scores on both FOUR and GCS was higher than the hospital mortality rate. CONCLUSION: Considering that FOUR score allows a more detailed neurological evaluation than GCS, and our findings suggest that FOUR score is more useful for patients who are unconscious or dependent on mechanical ventilation.


Subject(s)
Glasgow Coma Scale , Trauma Severity Indices , Unconsciousness/diagnosis , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Neurologic Examination/methods , Prospective Studies , Reproducibility of Results , Young Adult
13.
Pain Res Manag ; 2017: 8431823, 2017.
Article in English | MEDLINE | ID: mdl-28912639

ABSTRACT

OBJECTIVES: We aimed to assess the effects of levobupivacaine and of levobupivacaine + adrenaline administered during pediatric tonsillectomy on the postoperative period. METHODS: A total of 90 patients between the ages of five and twelve were divided randomly into two groups before tonsillectomy: levobupivacaine only (0.5%) 0.4 mg·kg-1 or levobupivacaine (0.5%) 0.4 mg·kg-1 + adrenaline (1 : 200.000) administered by means of peritonsillar infiltration. Primary outcomes were postoperative pain scores recorded at various intervals until 24 hours postoperatively. Secondary outcomes included postoperative nausea and vomiting (PONV), time to first oral intake, time to the first administration of analgesics and total consumption of analgesics, and the amount of bleeding for all children. RESULTS: In both groups, patients had the same postoperative pain scores and PONV rates, and equal amounts of analgesics were consumed up to 24 hours postoperatively. The two groups also had the same time until first oral intake, recovery time and time to the first analgesic request, and amount of bleeding. CONCLUSIONS: Perioperative levobupivacaine infiltration on its own is a valid alternative to the combination of levobupivacaine + adrenaline for perioperative and postoperative effectiveness in pediatric tonsillectomy. This trial is registered with Australian New Zealand Clinical Trial Registry ACTRN: ACTRN12617001167358.


Subject(s)
Bupivacaine/analogs & derivatives , Epinephrine/therapeutic use , Pain, Postoperative/drug therapy , Tonsillectomy , Analgesics/administration & dosage , Analgesics/therapeutic use , Anesthetics, Local/administration & dosage , Anesthetics, Local/therapeutic use , Bupivacaine/administration & dosage , Bupivacaine/therapeutic use , Child , Child, Preschool , Double-Blind Method , Epinephrine/administration & dosage , Female , Humans , Levobupivacaine , Male
14.
BMC Anesthesiol ; 17(1): 97, 2017 Jul 17.
Article in English | MEDLINE | ID: mdl-28716040

ABSTRACT

BACKGROUND: Patients in intensive care units (ICUs) are often physically unable to communicate with their physicians. Thus, the sharing of information about the on-going treatment of the patients in ICUs is directly related to the communication attitudes governing a patient's relatives and the physician. This study aims to analyze the attitudes displayed by the relatives of patients and the physician with the purpose of determining the communication between the two parties. METHODS: For data collection, two similar survey forms were created in context of the study; one for the relatives of the patients and one for the ICU physicians. The questionnaire included three sub-dimensions: informing, empathy and trust. The study included 181 patient relatives and 103 ICU physicians from three different cities and six hospitals. RESULTS: Based on the results of the questionnaire, identification of the mutual expectations and substance of the messages involved in the communication process between the ICU patients' relatives and physicians was made. The gender and various disciplines of the physicians and the time of the conversation with the patients' relatives were found to affect the communication attitude towards the patient. Moreover, the age of the patient's relatives, the level of education, the physician's perception, and the contact frequency with the patient when he/she was healthy were also proven to have an impact on the communication attitude of the physician. CONCLUSION: This study demonstrates the mutual expectations and substance of messages in the informing, empathy and trust sub-dimensions of the communication process between patient relatives and physicians in the ICU. The communication between patient relatives and physicians can be strengthened through a variety of training programs to improve communication skills.


Subject(s)
Attitude of Health Personnel , Communication , Family/psychology , Intensive Care Units , Professional-Family Relations , Adult , Empathy , Female , Humans , Male , Middle Aged , Trust/psychology , Young Adult
15.
Eplasty ; 15: e15, 2015.
Article in English | MEDLINE | ID: mdl-25987940

ABSTRACT

BACKGROUND: Following breast reduction procedures, the level of postoperative pain can be severe, and sufficient pain control influences a patient's physiological, immunological, and psychological status. OBJECTIVE: The aim of this study was to examine the use of intrathecal morphine (ITM) in breast reduction surgery with patient-controlled analgesia (PCA). METHODS: Sixty-two female patients who underwent breast reductions with the same technique participated in this study. The study group (ITM + PCA) included 32 patients; a single shot (0.2 mg) of ITM and intravenous morphine with PCA were administered. In the control group, morphine PCA alone was intravenously administered to 30 patients. Comparisons between the groups of cumulative morphine consumption, visual analog scale scores, and patient satisfaction scores, which were the primary outcome measures, and adverse effects, which were the secondary outcome measures, were conducted. RESULTS: The patients in the 2 groups had similar degrees of pain and satisfaction scores. The study group had lower cumulative morphine consumption (P = .001) than the PCA-only control group; there was no statistically significant difference in adverse effects between the 2 groups. CONCLUSION: Intrathecal morphine may effectively control pain with lower total morphine consumption following breast reduction surgery.

16.
Pain Med ; 15(5): 772-81, 2014 May.
Article in English | MEDLINE | ID: mdl-24612225

ABSTRACT

OBJECTIVE: We aimed to determine Axis-I psychiatric disorders in patients with chronic pain (CP) and compare control subjects determined by a structured clinical interview. Another objective of the study was to examine whether there is an association between psychiatric disorders and quality of sleep, quality of life, and demographic and clinical characteristics in patients with CP. DESIGN: The study sample was comprised of 108 patients with CP and 54 control subjects without pain. Psychiatric interviews were conducted with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV (SCID). Also used were the Hospital Anxiety and Depression Scale, Hamilton Depression Inventory, Short Form-36, and Pittsburgh Sleep Quality Index (PSQI). RESULTS: The rate of any Axis-I psychiatric disorder stood at 66.7% (any mood disorder, 50%; any anxiety disorder, 33.3%; any somatoform disorder, 20.4%; any substance use disorder, 16.6%), significantly more common in the patients' group compared with the control group. The most common psychiatric disorder was major depression (49.1%) in subjects with CP. Female gender, numbers of localization, and neck and back localizations were significantly higher in the SCID (+) group than the SCID (-) group. A statistically significant difference was observed between the SCID (+) and SCID (-) groups regarding visual analogue scale, depression and anxiety scores, mental component summary score, and global PSQI scores. CONCLUSION: Results of this study suggest that psychiatric morbidity in patients with CP is frequently seen and may adversely affect quality of sleep and quality of life of the patients. Therefore, the patients with CP should be examined with respect to their mental status.


Subject(s)
Chronic Pain/epidemiology , Mental Disorders/epidemiology , Quality of Life/psychology , Sleep Wake Disorders/epidemiology , Adult , Aged , Anxiety Disorders/epidemiology , Anxiety Disorders/psychology , Chronic Pain/psychology , Comorbidity , Depressive Disorder/epidemiology , Depressive Disorder/psychology , Diagnostic and Statistical Manual of Mental Disorders , Female , Humans , Linear Models , Male , Mental Disorders/psychology , Middle Aged , Mood Disorders/epidemiology , Mood Disorders/psychology , Pain Measurement , Psychiatric Status Rating Scales , Sleep , Sleep Wake Disorders/psychology , Somatoform Disorders/epidemiology , Somatoform Disorders/psychology , Substance-Related Disorders/epidemiology , Substance-Related Disorders/psychology
17.
Fundam Clin Pharmacol ; 28(2): 205-10, 2014 Apr.
Article in English | MEDLINE | ID: mdl-23127168

ABSTRACT

This study was designed to investigate whether dexketoprofen added to perineuraly or subcutaneously alters the effects of levobupivacaine in a rat model of sciatic nerve blockade. Thirty-six rats received unilateral sciatic nerve blocks along with a subcutaneous injection by a blinded investigator assigned at random. Combinations were as follows: Group 1 (sham) perineural and subcutaneous saline; Group 2, perineural levobupivacaine alone and subcutaneous saline; Group 3, perineural levobupivacaine plus dexketoprofen and subcutaneous saline; Group 4, perineural levobupivacaine and subcutaneous dexketoprofen; Group 5, perineural dexketoprofen and subcutaneous saline; and Group 6, perineural saline and subcutaneous dexketoprofen. The levobupivacaine concentration was fixed at 0.05%, and the dose of dexketoprofen was 1 mg kg(-1) . Sensory analgesia was assessed by paw withdrawal latency to a thermal stimulus every 30 min. The unblocked paw served as the control for the assessment of systemic, centrally mediated analgesia. Perineural and subcutaneous dexketoprofen coadministered with perineural levobupivacaine did not enhance the duration of sensory blockade when compared with levobupivacaine alone. There were significant differences between the operative and control paws for time points 30-90 min in the perineural levobupivacaine alone, levobupivacaine + dexketoprofen and subcutaneous dexketoprofen added levobupivacaine group. Significant differences were not determined between the levobupivacaine alone group and dexketoprofen added groups in operative paw. The effects of dexketoprofen are unknown for perineural administration. There is no significant difference between the analgesic effects of peripheral nerve blocks using levobupivacaine alone and plus subcutaneous or perineural dexketoprofen.


Subject(s)
Analgesia/methods , Anesthetics, Local/pharmacology , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Autonomic Nerve Block/methods , Bupivacaine/analogs & derivatives , Ketoprofen/analogs & derivatives , Sciatic Nerve/drug effects , Tromethamine/pharmacology , Anesthetics, Local/administration & dosage , Animals , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Bupivacaine/pharmacology , Hot Temperature , Injections, Subcutaneous , Ketoprofen/administration & dosage , Ketoprofen/pharmacology , Levobupivacaine , Pain Measurement , Rats , Rats, Sprague-Dawley , Time Factors , Tromethamine/administration & dosage
19.
Ren Fail ; 35(5): 761-5, 2013.
Article in English | MEDLINE | ID: mdl-23650892

ABSTRACT

Ultrasound-guided right internal jugular vein catheterization (RIJV) should be the first choice to decrease the catheter-related complications in high-risk hemodialysis patients. For this procedure, clinicians should identify the optimum positions of the RIJV, including its lower overlap with the carotid artery (CA) and high cross-sectional area of the vein. The aim of this prospective randomized study to evaluate the effects of mild ipsilateral head rotation combined with Trendelenburg position on RIJV cross-sectional area and its relation to the CA in adult patients. Forty ASA I-II patients who were undergoing elective surgery were enrolled for this study. The subjects were asked to remain supine in the 15-20° Trendelenburg position. Two-dimensional ultrasound was then used to measure the degree of overlap between the RIJV and CA, the cross-sectional area of the RIJV. These measurements were compared between head rotation to the >30° left, <30° left, neutral, and <30° right positions. When the head was in the >30° left position, overlap was seen in 38 of 40 patients (95%). As the head was rotated from >30° left to <30° right, the CA-RIJV overlap (from 95% to 57.5%), and the cross-sectional area (from 14.2 mm to 8.7 mm) significantly decreased. In conclusion, when the head was turned to <30° right, the CA-RIJV overlap significantly decreased, and the cross-sectional area also decreased. When clinicians determine the optimal head position before RIJV cannulation, it is important to consider the advantages and disadvantages of the different head positions from >30° left to <30° right.


Subject(s)
Catheterization, Central Venous/methods , Jugular Veins/surgery , Adult , Carotid Arteries , Female , Humans , Male , Middle Aged , Prospective Studies , Young Adult
20.
Agri ; 25(2): 47-54, 2013.
Article in Turkish | MEDLINE | ID: mdl-23720078

ABSTRACT

OBJECTIVES: We aimed to compare the effects of ketamine and tramadol administered intraoperatively on postoperative pain and analgesic demand in children undergoing tonsillectomy operations. METHODS: Ninety children undergoing tonsillectomy, aging 5-15 years old, with ASA I - II , were included in this study. Cases were arranged in three groups and given standardized general anesthesia. After coagulation, ketamine (0.5 mg.kg-1) was administered intravenously (iv) in the ketamine group, and tramadol iv (2 mg.kg-1) was given in the tramadol group and the control group received a physiologic iv. The duration of anesthesia, duration of operation, and length of stay in the PACU were recorded. NRS and CHEOPS scales were used to assess postoperative pain. Paracetamol (15 mg.kg-1) was given rectally in the first 6 hours (hrs) and orally over the subsequent 6 hrs, if NRS greater than 3 and CHEOPS greater than 8 were observed. All data were recorded concerning the initial and total dosage of analgesic and the presence of complications within 24 hrs. RESULTS: Demographic data, duration of anesthesia, duration of operation, and duration of stay in the PACU were similar between groups (p>0.05). The number of patients requiring additive analgesic was higher in the control group. No differences were found between the tramadol and ketamine groups (p>0.05). Additional analgesic was given earlier in the control group (p<0.05), but the need for additional analgesic was similar in tramadol and ketamine groups (p>0.05). Paracetamol dosage was significantly higher in the control group (p<0.05), but similar between the tramadol and ketamine groups (p>0.05). The frequency of nausea and vomiting was found to be significantly higher in tramadol and ketamine groups compared to the control group (p<0.05). CONCLUSION: Postoperative pain was effectively managed using 2 mg.kg-1 tramadol and 0.5 mg.kg-1 ketamine in pediatric tonsillectomies.


Subject(s)
Analgesics, Opioid/administration & dosage , Analgesics/administration & dosage , Ketamine/administration & dosage , Pain, Postoperative/prevention & control , Tonsillectomy , Tramadol/administration & dosage , Adolescent , Child , Child, Preschool , Drug Administration Schedule , Female , Humans , Intraoperative Period , Length of Stay , Male , Treatment Outcome
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