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J Craniofac Surg ; 25(1): 98-102, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24240769

ABSTRACT

Over the past 60 years, many surgical techniques have been developed for the repair of nasoseptal perforations. This study describes a safe and practical technique involving the 5-layer repair of symptomatic nasoseptal perforations without mucosal flaps. The present study involved 23 patients (17 men and 6 women) who had symptomatic nasoseptal perforations in the Otorhinolaryngology and Head Neck Surgery Department of Haseki Research and Training Hospital. Patients were treated using the mucosal regeneration technique. Follow-up examinations were performed at 3 and 6 months postoperatively. The surgery was considered successful if total closure was achieved. Nasal mucosal physiology was also assessed preoperatively and at 3 and 6 months postoperatively by measuring the nasal mucociliary clearance time by means of the saccharin test. The most common etiological factor was former nasal surgery (56.5%), followed by nasal trauma (26%). In 4 patients (17.5%), the perforations were idiopathic. The average preoperative perforation size was 1.74 ± 0.87 cm. Total closure of the perforation was achieved in 21 patients (91.3%), and only 2 patients had subtotal healing. The mean preoperative mucociliary clearance time was 19.3 ± 4.15 minutes, which significantly improved to 12.4 ± 3.53 minutes and 10.1 ± 3.21 minutes at 3 and 6 postoperative months, respectively. Mucosal regeneration technique with interpositional grafts can be used to safely and reliably repair medium-to-large nasoseptal perforations.


Subject(s)
Cartilage/transplantation , Nasal Septal Perforation/surgery , Adult , Ear Cartilage/surgery , Female , Follow-Up Studies , Humans , Male , Middle Aged , Mucociliary Clearance/physiology , Nasal Mucosa/physiology , Nasal Septum/surgery , Regeneration/physiology , Rhinoplasty/methods , Surgical Flaps/surgery , Tissue and Organ Harvesting/methods , Transplant Donor Site/surgery , Wound Healing/physiology
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