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Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system.
Allmond, Leonard R; Karaca, Timur J; Nguyen, Vinh N; Nguyen, Thong; Wiener-Kronish, Jeanine P; Sawa, Teiji.
Infect Immun ; 71(4): 2230-3, 2003 Apr.
Article in English | MEDLINE | ID: mdl-12654846

ABSTRACT

Of the proteins encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system, PcrG bound to PcrV and PcrH bound to PopB/PopD. In addition, Yersinia LcrG bound to PcrV, and Yersinia LcrH bound to PopD. The results imply a highly functional conservation of type III secretion between P. aeruginosa and Yersinia species.


Subject(s)
Bacterial Proteins/metabolism , Pseudomonas aeruginosa/metabolism , Animals , Antigens, Bacterial/genetics , Antigens, Bacterial/metabolism , Bacterial Proteins/genetics , Bacterial Toxins/genetics , Bacterial Toxins/metabolism , Gene Expression Regulation, Bacterial , Immunoblotting , Mice , Operon , Pore Forming Cytotoxic Proteins , Protein Binding , Pseudomonas aeruginosa/genetics , Rabbits , Yersinia/genetics , Yersinia/metabolism
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