ABSTRACT
An interesting case of perineal recurrence of rectal cancer after abdomino-perineal rectal amputation according to Miles is reported and it is emphasized how local recurrences after radical operations are a serious problem due to their frequency, the seriousness of the situation and scarce therapeutical possibilities available. The etiopathogenetical and clinical-therapeutical aspects were examined with respect to the problems of rectal neoplastic recurrence and it was noted that only aggressive surgical action, only in a very limited group of patients, increases survival, offering substantial advantages in terms of quality of life with respect to alternative therapies that have proved ineffective. The prevention of recurrence can only be achieved with suitable surgical and adjuvant medical treatment which together with an early diagnosis of the neoplastic recurrence are necessary to obtain best results.
Subject(s)
Neoplasm Recurrence, Local , Rectal Neoplasms/surgery , Fatal Outcome , Female , Humans , Middle Aged , PerineumABSTRACT
The Authors report their experience in the treatment of bleeding gastric and duodenal ulcers by means of endoscopic sclerotherapy. From August 1988 to December 1989, 104 patients with haematemesis and/or melena were observed at the Clinica Chirurgica Generale, Toracica e Vascolare-Università di Parma. Endoscopy, carried out in the first 24 hours, led to the diagnosis of a bleeding gastric or duodenal ulcer in 73 cases; 22 of these patients underwent emergency sclerotherapy using 1:10,000 Adrenaline in association with 1% Polydocanol. Results obtained are the following: absolute haemostasis in 20 patients (91%), and surgical intervention in the other 2 cases for renewed haemorrhage. Among patients endoscopically treated, one death (5%) was recorded. Further complications were not encountered. The Authors believe sclerotherapy is reliable and quick thus representing a considerable therapeutic advance in the treatment of gastroduodenal haemorrhage, notoriously at high death rate (8-10%).