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[The new possibilities in serologic diagnostic of Ixodes mite-borne borreliosis using ImmunoChip].
Chekanova, T A; Markelov, M L; Karan', L C; Ushakova, M A; Pudova, E A; Romashkina, A C; Kirdiashkina, N P; Manzeniuk, I N; Sazhin, A I; Snarkaia, E C; Anan'eva, L P; Shipulin, G A.
Klin Lab Diagn ; (12): 51-5, 2013 Dec.
Article in Russian | MEDLINE | ID: mdl-24757867

ABSTRACT

The new kit of reagents in format of the immunochip "ImmunoChip Borreliosis" for multiplex serologic analysis of mite-borne borreliosis demonstrated high diagnostic sensitivity and specificity. The percentage of detection of specific immunoglobulins was higher in "ImmunoChip Borreliosis" as compared with screening results in immune enzyme analysis. The high correlation between results of testing in immunochip and data of immune blotting is demonstrated to.


Subject(s)
Borrelia burgdorferi/isolation & purification , Ixodes/microbiology , Lyme Disease/diagnosis , Lyme Disease/microbiology , Animals , Antibodies, Bacterial/blood , Antibodies, Bacterial/immunology , Antibodies, Bacterial/isolation & purification , Borrelia burgdorferi/pathogenicity , Humans , Immunoglobulin G/blood , Immunoglobulin G/isolation & purification , Immunoglobulin M/blood , Immunoglobulin M/isolation & purification , Lyme Disease/blood , Lyme Disease/immunology , Sensitivity and Specificity , Serologic Tests/methods
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