ABSTRACT
PURPOSE: The study sought to evaluate the potential of diffusion-weighted magnetic resonance imaging to detect changes in liver diffusion in benign and malignant distal bile duct obstruction and to investigate the effect of the choice of b-values on apparent diffusion coefficient (ADC). METHODS: Diffusion-weighted imaging was acquired with b-values of 200, 600, 800, and 1000 s/mm2. ADC values were obtained in 4 segments of the liver. The mean ADC values of 16 patients with malignant distal bile duct obstruction, 14 patients with benign distal bile duct obstruction, and a control group of 16 healthy patients were compared. RESULTS: Mean ADC values for 4 liver segments were lower in the malignant obstruction group than in the benign obstruction and control groups using b = 200 s/mm2 (P < .05). Mean ADC values of the left lobe medial and lateral segments were lower in the malignant obstruction group than in the benign obstructive and control groups using b = 600 s/mm2 (P < .05). Mean ADC values of the right lobe posterior segment were lower in the malignant and benign obstruction groups than in the control group using b = 1000 s/mm2 (P < .05). Using b = 800 s/mm2, ADC values of all 4 liver segments in each group were not significantly different (P > .05). There were no correlations between the ADC values of liver segments and liver function tests. CONCLUSION: Measurement of ADC shows good potential for detecting changes in liver diffusion in patients with distal bile duct obstruction. Calculated ADC values were affected by the choice of b-values.
Subject(s)
Carcinoma/diagnostic imaging , Cholestasis, Intrahepatic/diagnostic imaging , Cholestasis, Intrahepatic/etiology , Diffusion Magnetic Resonance Imaging , Digestive System Neoplasms/diagnostic imaging , Digestive System Neoplasms/pathology , Aged , Aged, 80 and over , Carcinoma/complications , Cholelithiasis/complications , Cholelithiasis/diagnostic imaging , Diffusion Magnetic Resonance Imaging/methods , Digestive System Neoplasms/complications , Female , Humans , Male , Middle Aged , Pancreatitis/complications , Pancreatitis/diagnostic imaging , Retrospective StudiesABSTRACT
PURPOSE: To evaluate the correlations between the apparent diffusion coefficient (ADC) value and the standardized uptake value (SUV) with prognostic factors in breast cancer. MATERIALS AND METHODS: Seventy women with invasive breast cancer (56 cases of invasive ductal carcinoma, four of mixed ductal and lobular invasive carcinoma, three of lobular invasive carcinoma, two of micropapillary carcinoma, and one each of mixed ductal and mucinous carcinoma, mucinous carcinoma, medullary carcinoma, metaplastic carcinoma, and tubular carcinoma) were included in this study. All patients underwent presurgical breast magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI) at 1.5T and whole-body (18) F-fluorodeoxyglucose ((18) F-FDG) positron emission tomography (PET) / computed tomography (CT). For all invasive breast cancers and invasive ductal carcinomas, we assessed the relationships among ADC, SUV, and pathological prognostic factors. RESULTS: Both the median ADC value and maximum SUV (SUVmax) were significantly associated with vascular invasion (P = 0.008 and P = 0.026, respectively). SUVmax was also significantly correlated with tumor size (P = 0.001), histological grade (P = 0.001), lymph node status (P = 0.0015), estrogen receptor status (P = 0.010), and human epidermal growth factor receptor 2 status (P = 0.020), whereas ADC values were not. The correlation between the ADC and SUVmax was not significant (P = 0.356; R = -0.112). Mucinous carcinoma showed high ADC and relatively low SUVmax. Medullary carcinoma showed low ADC and high SUVmax. When we evaluated the relationships among ADC, SUVmax, and prognostic factors in the 56 invasive ductal carcinomas, our statistical results were not significantly changed, except SUVmax was also significantly associated with progesterone receptor status (P = 0.034), but not lymph node status. CONCLUSION: SUVmax may be valuable for predicting the prognosis of breast cancer. Both ADC and SUVmax are useful to predict vascular invasion. J. Magn. Reson. Imaging 2016;43:1434-1444.
Subject(s)
Breast Neoplasms/diagnostic imaging , Diffusion Magnetic Resonance Imaging/methods , Fluorodeoxyglucose F18 , Image Enhancement/methods , Image Interpretation, Computer-Assisted/methods , Positron Emission Tomography Computed Tomography/methods , Adult , Aged , Female , Humans , Mammography/methods , Middle Aged , Prognosis , Radiopharmaceuticals , Reproducibility of Results , Sensitivity and SpecificityABSTRACT
This pictorial essay presents the common radiological (mammography and/or ultrasonography) and pathological findings observed in unusual malignant breast lesions, which include well-differentiated subtypes of invasive ductal carcinoma not otherwise specified (tubular, mucinous, papillary, and medullary carcinomas), metaplastic carcinoma, and metastases. This study also includes unusual ultrasonographic appearances of a plasmacytoma.
Subject(s)
Breast Neoplasms/pathology , Breast Neoplasms/diagnostic imaging , Female , Humans , Middle Aged , Radiography , UltrasonographyABSTRACT
Pulsation on the bone cortex surface is a rare condition. Pulsative palpation of the superficial-located bone tumors can be misperceived as an aneurysm. Fifty-eight-year-old man is presented with pulsating bone mass in his proximal tibia. During angiographic examination, hypervascular masses were diagnosed both at right kidney and at right proximal tibia. Renal cell carcinoma was diagnosed after abdominal CT scan. Proximal tibia biopsy was complicated with projectile bleeding.
