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Curr Atheroscler Rep ; 24(2): 97-108, 2022 02.
Article in English | MEDLINE | ID: mdl-35107762

ABSTRACT

PURPOSE OF REVIEW: Intravascular imaging systems can identify lipid-rich and vulnerable plaques and help in treatment guidance. The comparability of different intracoronary imaging methods remains unclear. In this paper, we review atherosclerotic plaque pathology, plaque-stabilising effects of different lipid-lowering therapies and usage of intravascular imaging modalities. We present the results of our study in which we evaluated the correlation of the intravascular ultrasound iMAP system (iMAP-IVUS) and near-infrared spectroscopy (NIRS) in the diagnosis of vulnerable coronary plaques. RECENT FINDINGS: Lipids have an essential contribution to plaque evolution and vulnerability. Increase in plaque vulnerability alone even without increase in plaque burden defines progression of atherosclerosis. Lipidic tissue has a significant diagnostic value in patient risk stratification and can serve as a treatment target. Different vulnerable plaque parameters can be visualised with iMAP-IVUS and NIRS. Intravascular imaging systems can differ with regard to their sensitivity, specificity and limitations. Lipid-lowering therapy is crucial in plaque stabilisation.


Subject(s)
Coronary Artery Disease , Plaque, Atherosclerotic , Coronary Artery Disease/diagnostic imaging , Coronary Vessels/diagnostic imaging , Coronary Vessels/pathology , Humans , Lipids , Plaque, Atherosclerotic/diagnostic imaging , Spectroscopy, Near-Infrared/methods , Ultrasonography, Interventional/methods
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