ABSTRACT
A complex of restorative treatment measures applied for promoting the process of motor function restoration in patients who underwent removal of parasagittal meningiomas includes drug therapy, physiotherapy, and therapeutic exercises. The lapse of time after the operation and the specific features of the motor defect must be taken into account. The suggested complex was used in 87 patients. Motor activity was restored in 23 patients completely and to a satisfactory degree in 49 patients. The causes of poor outcomes are analysed. Optimum rehabilitation of neurosurgical patients can be achieved only with complex and stage-by-stage restorative treatment.
Subject(s)
Meningeal Neoplasms/surgery , Meningioma/surgery , Movement Disorders/rehabilitation , Adult , Combined Modality Therapy , Drug Therapy, Combination , Electric Stimulation Therapy , Exercise Therapy , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local , Postoperative Complications/rehabilitation , Vibration/therapeutic useABSTRACT
Specific features of motor activity disorders were studied in 87 patients before and after removal of a parasagittal meningioma. Motor disorders are most severe in localization of the tumor in the region of the middle third of the superior sagittal sinus and falx and less severe when the tumor is found in the posterior parts of the anterior third of the superior sagittal sinus. The disorders are more marked after operation with extensive resection of areas of the superior sagittal sinus involves in the tumor and with occlusion of the formed venous drainage passages. The motor disorders are particularly severe after removal of parasagittal meningiomas and are often bilateral with multiple components (including disturbances in the pyramidal and extrapyramidal systems, afferent regulation of movements, and coordinated work of both hemispheres in the formation of motor acts). Not only the direct effect of the pathological focus on the cerebral motor zones situated at different levels but disorders of cerebral and peripheral circulation are of importance in the pathogenesis of these disturbances.
Subject(s)
Brain Neoplasms/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Paralysis/etiology , Adult , Aged , Cerebrovascular Circulation , Electroencephalography , Female , Humans , Male , Middle Aged , Paralysis/physiopathology , Plethysmography, Impedance , Postoperative Complications/etiology , Postoperative Complications/physiopathologySubject(s)
Brain Injuries/drug therapy , Glutamates/administration & dosage , Mental Processes , Administration, Intranasal , Adult , Brain Concussion/drug therapy , Brain Injuries/psychology , Cerebral Hemorrhage/therapy , Dominance, Cerebral , Female , Glutamic Acid , Humans , Iontophoresis , Male , Middle Aged , Skull/injuriesABSTRACT
Endonasal electrophoresis with alpha-glutamic acid was used in 76 patients with severe craniocerebral injury. The result was good in 24 (38%) and satisfactory in 40 (55%) patients. Thus, a positive result of treatment was obtained in 88% of cases, which was confirmed by electrophysiological and neuropsychological studies. The method produced the greatest effect on the patients' psychic status: 74% of all disorders of higher psychic functions, mainly memory, were restored on the average by the end of treatment. Good tolerance of electrophoresis and its efficacy in the early period after severe injury, i. e. in the first month, were established. Contraindications for treatment were defined more precisely. Since the method is simple and does not call for special conditions, it may be widely used in any medical establishment equipped with galvanization apparatuses.
Subject(s)
Brain Injuries/drug therapy , Glutamates/administration & dosage , Administration, Intranasal , Adult , Aged , Aminophylline/administration & dosage , Aminophylline/therapeutic use , Electroencephalography , Electrophoresis , Epilepsy, Post-Traumatic/prevention & control , Glutamates/therapeutic use , Glutamic Acid , Humans , Middle Aged , Movement Disorders/drug therapy , Neurocognitive Disorders/drug therapy , Sleep Wake Disorders/drug therapySubject(s)
Arachnoiditis/drug therapy , Iontophoresis , Papain/administration & dosage , Adolescent , Adult , Child , Child, Preschool , Chronic Disease , Chymopapain , Drug Combinations , Drug Evaluation , Female , Humans , Male , Meningitis/drug therapy , Middle AgedABSTRACT
A possibility of providing local hypothermia for human extremities over the area from 6.25 cm2 to 37.5 cm2 with temperature level up to 10 degrees C is shown. "Gipospast-1" is designed for accomplishing the local hypothermia. It was revealed that at such conditions the human organism reaction ensures a specific heat flow on the cooling surface to 0.02+/-0.04 W/cm2. The clinical trials of the apparatus confirmed its efficacy for removing the contractures of the facial muscles and for decreasing the spastics in paretic extremities of neurosurgical patients.
Subject(s)
Hypothermia, Induced/instrumentation , Body Temperature , Evaluation Studies as Topic , Humans , Semiconductors , Thermal ConductivityABSTRACT
The report contains data concerning occupational and social rehabilitation of 46 patients operated on for aneurysma of the anterior communicative artery. It was established that the occupational prognosis depends upon the severity of the hemmorhage, character of surgical operation. Of significance are the conditions of work, time after the surgical operation. The authors mark that in 2/3 of the operated on patients the working capacity is being restored. A spontaneous restoration of diaturbed functions is slow and is not always sufficient. With this purpose it is expedient to repeat courses of a general tonic and special rehabilitative therapy. A favourable factor in the readaptation of patients is their early engagement in working activities. The authors give their recommendations for medical labour expert testimony for this category of patients.
Subject(s)
Circle of Willis , Intracranial Aneurysm/rehabilitation , Adolescent , Adult , Child , Follow-Up Studies , Hemiplegia/complications , Humans , Intracranial Aneurysm/complications , Intracranial Aneurysm/surgery , Memory Disorders/etiology , Middle Aged , Postoperative Complications , Rehabilitation, Vocational , Social Adjustment , Subarachnoid Hemorrhage/complicationsABSTRACT
The chemical structure of a galascorbine molecule was studied by the nuclear magnetic resonance NMR technique. On the basis of the obtained NMR spectra a conclusion was drawn than galascorbine is ester ascorbic acid and tannin hydroxycarbon acids. This finding was confirmed by the results of independent studies in the products of interaction between ascorbic and gallic acids.