ABSTRACT
A 70-year-old Indian woman presented with an acute anterior wall myocardial infarction and a large multinodular goiter causing tracheal compression and dyspnea. Coronary artery angiography revealed severe triple-vessel disease, with an 80% occlusion of the left main stem, necessitating early coronary artery bypass grafting combined with total thyroidectomy. The procedure was performed successfully. At the 1-year follow-up, the patient remains euthyroid and in New York Heart Association functional class I. This case provides further evidence that combined coronary artery bypass grafting and total thyroidectomy is both feasible and safe.
Subject(s)
Coronary Artery Bypass, Off-Pump , Goiter, Nodular/epidemiology , Myocardial Infarction/epidemiology , Thyroidectomy , Aged , Comorbidity , Female , Goiter, Nodular/complications , Goiter, Nodular/diagnostic imaging , Goiter, Nodular/surgery , Humans , Myocardial Infarction/surgery , Tomography, X-Ray Computed , Tracheal Diseases/diagnostic imaging , Tracheal Diseases/etiologyABSTRACT
We explored the interrelationships of coagulation FVII activity levels with obesity, leptin and insulin resistance in diabetes mellitus (DM Type 2) and in non-diabetic control subjects. We found FVII hypercoagulant activity levels in DM not associated with obesity, leptin levels or insulin resistance. It was found independently associated with hypertriglyceridemia.
