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Trans R Soc Trop Med Hyg ; 108(5): 305-7, 2014 May.
Article in English | MEDLINE | ID: mdl-24598794

ABSTRACT

BACKGROUND: The study was undertaken to document the prevalence of Helicobacter pylori and endoscopic diagnoses in Rwandans presenting for gastroscopy. METHODS: We studied an endoscopic database containing 961 consecutive gastroscopy patients at the University Teaching Hospital, Butare, over 12 months. Patient characteristics, endoscopic diagnoses and H. pylori status (by modified rapid urease testing) were analysed. RESULTS AND CONCLUSION: The overall H. pylori positivity rate was 75% (n=825), similar to that found elsewhere in sub-Saharan Africa. Common endoscopic diagnoses included duodenal ulceration (20%), duodenitis (9%), benign gastric outlet obstruction (6%) and malignancy (5%). Duodenal ulceration was strongly associated with H. pylori infection (OR 6.2 [3.1-12.6]; p<0.001).


Subject(s)
Duodenal Ulcer/diagnosis , Duodenitis/diagnosis , Gastroscopy/statistics & numerical data , Helicobacter Infections/diagnosis , Helicobacter pylori/isolation & purification , Adult , Duodenal Ulcer/epidemiology , Duodenal Ulcer/etiology , Duodenal Ulcer/pathology , Duodenitis/epidemiology , Duodenitis/etiology , Duodenitis/pathology , Female , Helicobacter Infections/complications , Helicobacter Infections/epidemiology , Helicobacter Infections/pathology , Humans , Male , Middle Aged , Prevalence , Retrospective Studies , Rwanda/epidemiology , Tertiary Care Centers
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