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1.
Graefes Arch Clin Exp Ophthalmol ; 243(6): 619-21, 2005 Jun.
Article in English | MEDLINE | ID: mdl-15650855

ABSTRACT

PURPOSE: To report a case of retinal pigment epithelial tear treated by macular translocation with 360 degrees retinotomy. METHODS: Interventional case report. A 75-year-old woman with neovascular age-related macular degeneration and retinal pigment epithelial tear underwent macular translocation with 360 degrees retinotomy and silicone oil tamponade. After 3 months, pars plana vitrectomy, silicone oil removal, and muscle surgery were performed. RESULTS: Twenty-two months after macular translocation surgery, the visual acuity of the patient had improved to 20/50 (preoperative 20/200). No proliferative vitreoretinopathy or recurrence of the choroidal neovascularisation was observed. CONCLUSIONS: Macular translocation surgery with 360 degrees retinotomy can improve vision in retinal pigment epithelial tear secondary to neovascular age-related macular degeneration.


Subject(s)
Macula Lutea/transplantation , Retinal Perforations/surgery , Retinal Pigment Epithelium/pathology , Aged , Female , Fluorescein Angiography , Follow-Up Studies , Fundus Oculi , Humans , Laser Coagulation/methods , Lens Implantation, Intraocular , Phacoemulsification/methods , Retinal Perforations/diagnosis , Transplantation, Autologous , Vitrectomy/methods
2.
Graefes Arch Clin Exp Ophthalmol ; 243(3): 198-203, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15258778

ABSTRACT

BACKGROUND: To identify the frequency of new subfoveal hemorrhage and its impact on visual acuity 2 weeks following verteporfin photodynamic therapy (PDT) in the treatment of predominantly classic subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). METHODS: Retrospective, noncomparative, consecutive, interventional case series. At a tertiary retinal referral center, 104 eyes of 97 consecutive patients with predominantly classic subfoveal CNV were treated by PDT. Morphological outcomes include new subfoveal hemorrhage assessed on the photo review (pretreatment, 2 and 12 weeks after PDT). Visual acuity outcomes include moderate (3-5 ETDRS lines) and severe (6 and more ETDRS lines) loss of visual acuity at 2 weeks after PDT. RESULTS: In this study, 104 eyes of 97 patients were analyzed. CNV in all eyes was secondary to AMD. New subfoveal hemorrhage was found in 22% (23/104) of the eyes 2 weeks following PDT. 17.4% (4/23) of the eyes with new subfoveal hemorrhage had moderate or severe loss of visual acuity. In such eyes the 12-week examination revealed considerable resorption of the new subfoveal hemorrhage with some improvement of visual acuity. CONCLUSIONS: In 3.8% of the eyes that underwent PDT for predominantly classic subfoveal CNV secondary to AMD, new subfoveal hemorrhage may result in moderate or severe loss of visual acuity within 2 weeks. In all eyes with new subfoveal hemorrhage, considerable resorption of the hemorrhage and some improvement of the visual acuity were seen at 12 weeks. Candidates for PDT should be informed about the low risk of this complication.


Subject(s)
Choroidal Neovascularization/drug therapy , Photosensitizing Agents/adverse effects , Porphyrins/adverse effects , Retinal Hemorrhage/chemically induced , Aged , Aged, 80 and over , Choroidal Neovascularization/etiology , Choroidal Neovascularization/pathology , Female , Fluorescein Angiography , Fovea Centralis , Humans , Macular Degeneration/complications , Male , Middle Aged , Retinal Hemorrhage/pathology , Retinal Hemorrhage/physiopathology , Retrospective Studies , Time Factors , Verteporfin , Visual Acuity
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