ABSTRACT
Thymic seminoma is a rare clinical entity. We report a case of an 18-year-old male patient who presented with chest pain, dyspnea, dysphagia of 1-month duration. Contrast-enhanced computer tomogram of chest showed an anterior mediastinal mass. He was subjected to thoracotomy and excision of the mass. Histopathology examination revealed seminoma of thymus. He failed to follow up for a period of 8 months post-surgery as he was asymptomatic. He then presented with a recurrence of the tumor locally, along with metastases to the lung, para-aortic and peri-aortic lymph nodes. He was kept on cisplatin, bleomycin and etoposide.
ABSTRACT
We report a case of multiple extraosseous aneurysmal cysts occurring in the muscle and subcutaneous plane of postero-lateral aspects of the upper right leg. They appeared about 15 months after resection of aneurysmal bone cyst of the upper end of the fibula. They varied in size from 2 cm to 5 cm. Radiologically they were well-defined lesions with central septate areas surrounded by a rim of calcification. Histologically they showed central cystic spaces separated by septa consisting of fibroblasts, osteoclast type of giant cells and reactive woven bone. Thus they showed histological similarity with aneurysmal bone cysts, but did not show any connection with the bone. Only very few examples of aneurysmal cysts of soft tissue had been described in the past one decade and they were reported in various locations including rare sites such as arterial wall and larynx. Recent cytogenetic analyses have shown abnormalities involving 17p11-13 and/or 16q22 in both osseous and extraosseous aneurysmal cysts indicating its probable neoplastic nature. Our case had unique features like multiplicity and occurrence after resection of primary aneurysmal bone cyst of the underlying bone.
Subject(s)
Bone Neoplasms/diagnosis , Fibroma, Ossifying/diagnosis , Nasal Bone , Nose Neoplasms/diagnosis , Adult , Bone Neoplasms/surgery , Diagnosis, Differential , Endoscopy , Fibroma, Ossifying/surgery , Humans , Male , Nose Neoplasms/surgery , Otorhinolaryngologic Surgical Procedures/methods , Tomography, X-Ray ComputedABSTRACT
A case of 7 yr old boy with cerebellar melanotic medulloblastoma is reported. Melanotic medulloblastoma is a variant of medulloblastoma, which shares some of the histological features of Melanotic neuroectodermal tumor of infancy. However the predominant histological pattern and clinical behavior is that of conventional or classical medulloblastoma. The melanin pigments present in these tumors have been proved to be both neuromelanin and oculocutaneous type of melanin. This is a rare histological type and only few cases have been reported in the literature so far.
