[Causes of lethal outcomes in presenile and senile patients treated in pulmonological hospital]. / Prichiny letal'nykh iskhodov u lits pozhilogo i starcheskogo vozrasta v usloviiakh pul'monologicheskogo statsionara.

Causes of lethal outcomes were analysed for 46 patients (mean age 76.76 years, 39 males, or 84.78%, and 7 females, or 15.22%) why died of respiratory diseases when treated in War Veterans Hospital of St-Petersburg. Necropsies registered the following causes of death: chronic obstructive pulmonary disease (COPD) (32 deaths, 69.57%), cardiovascular diseases (17 deaths, 36.96%), cancer (14 deaths, 30.44%). Lethal outcomes were most frequent at the age of 71 to 80 years (52.17%). COPD was present in 43 of 46 of the deceased (93.48%). The most frequent direct causes of lethal outcomes in elderly patients with COPD were isolated pulmonary-cardiac insufficiency and combination of this insufficiency with pneumonia which is as an aggravating factor and determines the outcome of the basic disease.

[Functional status of the rat insular apparatus and adrenal cortex at early periods after irradiation]. / Funktsional'noe sostoianie insuliarnogo apparata i kory nadpochechnikov krys v rannie sroki posle oblucheniia.

As early as 0.5-3 h after X-irradiation of rats with a lethal dose of 12 Gy glucocorticoid activity of adrenal cortex was enhanced and 11-oxycorticosteroid level in blood was increased. The increasing of the immunoreactive insulin content of blood was registered at the background of hypercorticoidism and normal function of insular apparatus during the first hours following irradiation. At later times (24-72 h), a stable hypercorticoidism developed, the ability of beta-cells to react adequately to glucose was impaired, and IRI content of blood decreased.