ABSTRACT
The authors propose an original approach to the problem of intoxication syndrome observed in patients with acute intestinal infections (AII). They focus on such endogenic humoral antiendotoxic systems as Re-hemotype glycolipid antibodies and high-density lipoproteins. The titers of Re-antibodies in patients with light and moderate AII at the height of intoxication remained within control levels, whereas in patients with a severe AII course the titers values remained low throughout 7 days of the follow-up. Indometac administration induced changes in the antibodies formation. Lipoprotein endotoxin-binding activity persisted at low levels to the end of 7-day follow-up. Mechanisms involved in changing functional activity of the body antiendotoxic systems are considered.
