ABSTRACT
The problems of infusion therapy during anesthesia and surgery, relevant for clinical practice, have been reviewed. The changes in circulating blood volume, plasma osmolality and colloid-osmotic pressure have been studied depending on quantitative and qualitative structure of the infusion therapy as well as on the duration of surgical intervention. The dependence observed indicates that infusion therapy during anesthesia and surgery must not be considered a routine procedure. The data obtained will help practicing anesthesiologists to choose the right technique.
Subject(s)
Anesthesia , Blood Volume , Infusions, Parenteral , Osmotic Pressure , Colloids , Humans , Osmolar Concentration , Solutions , Surgical Procedures, OperativeABSTRACT
The value of such important parameters as colloid-osmotic pressure and osmolality of infusion media and their potential effect on the patient's body have been studied. The importance and necessity of dynamic control over the values of colloid-osmotic pressure and plasma osmolality in the course of infusion therapy have been stated. The problems of the correct choice of the infusion media depending on the concrete clinical situation have been reviewed.
Subject(s)
Colloids , Infusions, Parenteral , Osmotic Pressure , Blood Proteins/physiology , Blood Volume , Humans , Osmolar Concentration , SolutionsABSTRACT
The use of glucose-insulin mixture (0.5 g/(kg.h) glucose and 1 U/(kg.h) insulin) during preperfusion period in 26 cardiosurgical patients subject to cardiopulmonary bypass surgery prevented the disturbances in carbohydrate metabolism, reduced hemoglobin glycosylation, and normalized thromboxane-prostacyclin system functions, as compared to the data obtained in control groups.