ABSTRACT
The immunity status was studied in patients with acute pyo-destructive lung diseases complicated by purulent pleurisy (relative counts of T- and B-lymphocytes, subpopulation composition of T-cells, numbers of lymphocytes-killers, and functional state of neutrophils of the peripheral blood). These patients revealed significant cellular immunodeficiency, rise in B-lymphocytes, and apparent changes in the activity of the peripheral blood phagocytes. The endolymphatic drug route was found out to be superior to conventional ones in that it had more expressed normalizing action on the quantitative and functional state of T-lymphocytes, their subpopulation composition (manifested by augmentation of T-cells-helpers), as well as on the level of B-lymphocytes, lymphocytes-killers, and metabolic activity of neutrophils of the peripheral blood.
Subject(s)
Anti-Bacterial Agents/administration & dosage , Empyema, Pleural/drug therapy , Lung Diseases, Obstructive/drug therapy , B-Lymphocytes/drug effects , B-Lymphocytes/immunology , Empyema, Pleural/etiology , Empyema, Pleural/immunology , Humans , Immunity, Cellular/drug effects , Injections, Intralymphatic , Lung Diseases, Obstructive/complications , Lung Diseases, Obstructive/immunology , Lymphocyte Count/drug effects , T-Lymphocytes/drug effects , T-Lymphocytes/immunology , Time FactorsABSTRACT
Ultraviolet irradiation of blood studied in 201 patients with various forms of bronchial asthma proved to be the most effective in "aspirin" and infectious-allergic forms of the disease. Analysis of immunological changes showed that ultraviolet irradiation of blood brings to the norm content of IgG in serum, influence beneficially quantity and functional activity of T-lymphocytes, reduces auto-immunization and sensibilization to Streptococcus.