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Study of tumor-specific expression of some evolutionary new genes.

Krukovskaya, L L; Polev, D E; Kurbatova, T V; Karnaukhova, Y X; Kozlov, A P.

Vopr Onkol ; 62(3): 495-500, 2016.

Article in Russian | MEDLINE | ID: mdl-30463107

ABSTRACT

In this paper we have showed that evolutionary new genes DCD1(Dermicidin), LINC00309 (Long intergenic non-protein coding RNA 309) and CLLU1(Chronic lymphocytic leukemia up-regulated 1) have tumor-specific expression profile. Along with our previously published results this confirms the existence of the phenomenon of TSEEN (Tumor-Specifically Expressed, Evolutionarily Novel).

Subject(s)

Neoplasm Proteins/genetics , Neoplasms/genetics , Peptides/genetics , RNA, Long Noncoding/genetics , Biomarkers, Tumor/genetics , Evolution, Molecular , Female , Gene Expression Regulation, Neoplastic , Humans , Male , Neoplasms/classification , Neoplasms/pathology

ABSTRACT

Subject(s)

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