ABSTRACT
We found that tissue impedance can serve as a reliable criterion of the severity of wound process and efficiency of burn treatment. Ointment with superoxide dismutase effectively promoted wound reparation and recovery of tissue structure after thermal skin burn compared to ointments containing interleukin-1beta or mixture of interleukin-1beta and superoxide dismutase.
Subject(s)
Burns/drug therapy , Interleukin-1/therapeutic use , Superoxide Dismutase/therapeutic use , Animals , Burns/diagnosis , Electric Impedance , Interleukin-1/pharmacology , Male , Ointments/pharmacology , Ointments/therapeutic use , Rats , Skin/pathology , Superoxide Dismutase/pharmacology , Wound Healing/drug effectsABSTRACT
Effects of new wound dressing bacterial cellulose impregnated with SOD and poviargol (Procel-Super and Procel-PA) and Inerpan hydrogel dressing on the reparative processes in deep dermal burns (IIIa-IIIb degree) in rats exposed to total even irradiation in a dose of 4 Gy were studied. Inerpan and Procel-Super dressings proved to be the most effective under these conditions: they accelerated healing of burn wounds by 17.0 and 5.5%, respectively.