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1.

[Effect of a novel combined enterosorbent "Ultrasorb" on biochemical and morphologic blood parameters]. / Vliianie novogo kombinirovannogo énterosorbenta "Ul'trasorb" na biokhimicheskie i morfologicheskie pokazateli krovi.

Stavitskaia, S S; Kirsenko, V V; Karpenko, V N; Kartel', N T; Davydov, V I; Petrenko, T P; Gerasimenko, N V; Korviakova, S G.

Ukr Biokhim Zh (1978) ; 68(4): 95-100, 1996.

Article in Russian | MEDLINE | ID: mdl-9297307

ABSTRACT

In order to estimate toxicity of a novel composition, enterosorbent "ultrasorb", its toxic properties were studied in trials on experimental animals (white rats, mice, guinea pigs). Great variety of hematolytic, biochemical and pathohistologic parameters were determined to evaluate homeostasis. As a result of toxicity trials in acute and subacute experiments as well as in embryotoxic, teratogenic and allergic tests we have concluded that enterosorbent "Ultrasorb" is absolutely harmless and can be recommended for further trials in clinics.

Subject(s)

Blood Cells/drug effects , Enterosorption/methods , Animals , Drug Evaluation, Preclinical , Guinea Pigs , Hematocrit , Hematologic Tests , Hemoglobins/drug effects , Homeostasis/drug effects , Mice , Rats

2.

[The combined action of the organophosphate pesticide DDVP and ethanol]. / Kombinirovannoe deistvie fosfororganicheskogo pestitsida DDVF i étanola.

Karpenko, V N; Didenko, M N; Tashker, I D; Sokolova, N K.

Gig Sanit ; (1): 64-6, 1993 Jan.

Article in Russian | MEDLINE | ID: mdl-8339981

Subject(s)

Dichlorvos/toxicity , Ethanol/toxicity , Alcoholism/blood , Alcoholism/pathology , Animals , Drug Synergism , Male , Rats

3.

[Data on establishing the maximum permissible concentration of the herbicide levanil in the air of a work area]. / Materialy k obosnovaniiu predel'no dopustimoi kontsentratsii gerbitsida levanila v vozdukhe rabochei zony.

Karpenko, V N; Pokrovskaia, T N; Viter, V F.

Gig Tr Prof Zabol ; (7): 40-1, 1992.

Article in Russian | MEDLINE | ID: mdl-1296918

Subject(s)

Air Pollutants, Occupational/toxicity , Amides/toxicity , Herbicides/toxicity , Acute Disease , Air Pollutants, Occupational/poisoning , Amides/poisoning , Animals , Dose-Response Relationship, Drug , Female , Herbicides/poisoning , Lethal Dose 50 , Male , Maximum Allowable Concentration , Mice , Poisoning/pathology , Rats , Sex Characteristics , Skin/drug effects , Species Specificity

4.

[Ultrasonic scanning in the diagnosis of hepatic alveococcosis]. / Ul'trazvukovoe skanirovanie v diagnostike al'veokokkoza pecheni.

Zubovskii, G A; Karpenko, V N.

Med Radiol (Mosk) ; 34(6): 14-8, 1989 Jun.

Article in Russian | MEDLINE | ID: mdl-2661950

ABSTRACT

The echotomographic picture of liver alveococcosis was described on the basis of investigation of 132 patients (the diagnosis in 22 was verified by biopsy). Some features of alterations were determined over time. Radionuclide scanning was shown to be less effective in the diagnosis of liver alveococcosis than echotomography.

Subject(s)

Echinococcosis, Hepatic/diagnosis , Ultrasonography , Adult , Aged , Female , Humans , Male , Middle Aged

5.

[Substantiation of maximum permissible levels of mono-, di- and triisopropanolamine in the air of work areas]. / Materialy k obosnovaniiu predel'no dopustimykh kontsentratsii mono-, di- i triizopropanolamina v vozdukhe rabochei zony.

Burkatskaia, E N; Karpenko, V N; Pokrovskaia, T N; Ivanova, Z V; Medved', I L.

Gig Tr Prof Zabol ; (7): 46-8, 1986 Jul.

Article in Russian | MEDLINE | ID: mdl-3744114

Subject(s)

Air Pollutants, Occupational/toxicity , Chemical Industry , Propanolamines/toxicity , Animals , Female , Guinea Pigs , Maximum Allowable Concentration , Mice , Rabbits , Rats

6.

[Hygienic characteristics of the pesticide croneton]. / Materialy k gigienicheskoi kharakteristike pestitsida kronetona.

Karpenko, V N; Khokhol'kova, G A; Pokrovskaia, T N; Riazanova, R A; Gritsevskaia, I L.

Gig Sanit ; (10): 23-6, 1984 Oct.

Article in Russian | MEDLINE | ID: mdl-6519448

Subject(s)

Air Pollutants/toxicity , Carbamates/toxicity , Insecticides/toxicity , Animals , Body Weight/drug effects , Cats , Cholinesterases/blood , Embryo, Mammalian/drug effects , Female , Lethal Dose 50 , Mice , Mutagens , Pregnancy , Rabbits , Rats

7.

[Bases of the maximum allowable concentration of N, N-dimethyl-N'-(3-chlorophenyl)-guanidine in work environment]. / K obosnovaniiu PDK N, N-dimetil-N' (3-khlorfenil)-guanidina v vozdukhe rabochei zony.

Matiushina, V I; Karpenko, V N; Pokrovskaia, T N; Ivanova, Z V.

Gig Tr Prof Zabol ; (11): 56-7, 1983 Nov.

Article in Russian | MEDLINE | ID: mdl-6654135

Subject(s)

Guanidines , Herbicides , Maximum Allowable Concentration

8.

[Determination of maximum permissible exposure level for the herbicide vernam in the air of a working zone]. / Materialy k obosnovaniiu PDK gerbitsida vernama v vozdukhe rabochei zony.

Karpenko, V N; Aleksandrova, L G; Pokrovskaia, T N; Makarova, M L; Diadicheva, T V.

Gig Tr Prof Zabol ; (9): 49-50, 1983 Sep.

Article in Russian | MEDLINE | ID: mdl-6642234

Subject(s)

Air Pollutants, Occupational/toxicity , Herbicides/toxicity , Thiocarbamates/toxicity , Air Pollutants, Occupational/standards , Animals , Drug Evaluation, Preclinical , Herbicides/standards , Maximum Allowable Concentration , Rabbits , Rats

9.

[Blood coagulation disorders in pesticide poisoning]. / O narusheniiakh gemokoaguliatsii pri intoksikatsii pestitsidami.

Karpenko, V N.

Vrach Delo ; (12): 103-6, 1981 Dec.

Article in Russian | MEDLINE | ID: mdl-7331292

Subject(s)

Blood Coagulation Disorders/chemically induced , Pesticides/poisoning , Agricultural Workers' Diseases/chemically induced , Agricultural Workers' Diseases/physiopathology , Animals , Blood Coagulation/drug effects , Blood Coagulation Disorders/physiopathology , Female , Humans , Male , Rabbits , Rats , Time Factors

10.

[Data on the toxicological and hygienic characteristics of the new pesticide, pyrimor]. / Materialy k toksikologichno-gigienicheskoi kharakteristike novogo pestitsida pirimora.

Burkatskaia, E N; Karpenko, V N; Pokrovskaia, T N.

Gig Sanit ; (4): 8-11, 1980 Apr.

Article in Russian | MEDLINE | ID: mdl-7380281

Subject(s)

Carbamates , Insecticides/toxicity , Animals , Cats , Dose-Response Relationship, Drug , Environmental Exposure , Insecticides/poisoning , Lethal Dose 50 , Maximum Allowable Concentration , Mice , Rabbits , Rats , Skin Absorption/drug effects , Species Specificity , Time Factors

11.

[Changes of the blood vessels due to dithicarbamine pesticides]. / Izmeneniia sosudov pri vozdeistvii ditiokarbaminovykh pestitsidov.

Karpenko, V N; Matokhniuk, L A; Volkova, V M.

Vrach Delo ; (4): 131-3, 1978 Apr.

Article in Russian | MEDLINE | ID: mdl-664581

Subject(s)

Blood Vessels/drug effects , Pesticides/toxicity , Thiocarbamates/toxicity , Animals , Blood Vessels/pathology , Male , Rats

12.

The effect of pesticides--the derivatives of carbamic, thio-, and dithiocarbamic acids on warm-blooded animals.

Kundiev, Y I; Burkatskaya, E N; Karpenko, V N; Olefir, A I; Anina, I A.

Environ Qual Saf Suppl ; 3: 618-24, 1975.

Article in English | MEDLINE | ID: mdl-1063688

Subject(s)

Carbamates/pharmacology , Pesticides/pharmacology , Thiocarbamates/pharmacology , Animals , Cats , DNA/metabolism , Embryo, Mammalian/drug effects , Environmental Exposure , Female , Fetal Heart/metabolism , Gonads/drug effects , Immunity/drug effects , Lethal Dose 50 , Liver/metabolism , Maternal-Fetal Exchange , Pesticides/toxicity , Placenta/metabolism , Pregnancy , RNA/metabolism , Rabbits , Rats , Reproduction/drug effects

13.

[Effect of dithiocarbamcite pesticides, Cineb, Maneb and Polymarcin, on the blood coagulation system]. / Vliianie ditiokarbaminovykh pestitsidov Tsineba, Maneba i polimartsina na svertyvaiushchuiu sistemu krovi

Karpenko, V N.

Vrach Delo ; (1): 122-4, 1975 Jan.

Article in Russian | MEDLINE | ID: mdl-166518

Subject(s)

Blood Coagulation/drug effects , Ditiocarb/adverse effects , Fungicides, Industrial/adverse effects , Maneb/adverse effects , Thiocarbamates/adverse effects , Zineb/adverse effects , Animals , Rabbits , Thrombelastography , Thrombosis/chemically induced

14.

[Experimental data on establishing the maximum permissible concentration of polymarcine in the air of a work area]. / Eksperimental-nye materaly k obosnovaniiu predel'no dopustimoi kontsentratsii polimartsina v vozdukhe rabochei zony

Matokhniuk, L A; Karpenko, V N; Olefir, A I; Anina, I A.

Gig Sanit ; 0(9): 17-20, 1974 Sep.

Article in Russian | MEDLINE | ID: mdl-4420212

Subject(s)

Fungicides, Industrial/standards , Thiocarbamates/standards , Air Pollutants , Animals , Cats , Fungicides, Industrial/toxicity , Manganese , Maximum Allowable Concentration , Rabbits , Rats , Thiocarbamates/toxicity , Zinc

15.

[Allergenic effect of florimycin]. / Ob allergennom deistvii florimitsina.

Paustovskaia, V V; Krasnokutskaia, M B; Rappoport, M B; Karpenko, V N.

Vrach Delo ; 8: 99-102, 1972 Aug.

Article in Russian | MEDLINE | ID: mdl-4342150

Subject(s)

Drug Hypersensitivity/etiology , Viomycin/pharmacology , Allergens , Anaphylaxis/chemically induced , Animals , Blood Coagulation/drug effects , Guinea Pigs , Histamine/metabolism

16.

[Experimental data in substantiation of the maximum permissible concentration of tillam in the air of working zones]. / Eksperimental'nye dannye k obosnovaniiu predel'no dopustimoi kontsentratsii tillama v vozdukhe rabochei zony.

Voitenko, G A; Kaminskaia, T L; Karpenko, V N.

Gig Sanit ; 37(8): 104-5, 1972 Aug.

Article in Russian | MEDLINE | ID: mdl-4655687

Subject(s)

Environmental Health , Herbicides/toxicity , Animals , Cats , Female , Lethal Dose 50 , Male , Maximum Allowable Concentration , Mice , Rabbits , Rats

17.

[Effect of dinitrophenol pesticides on water-electrolyte metabolism indices]. / Vliianie dinitrofenol'nykh pestitsidov na pokazateli vodno-élektrolitnogo obmena.

Burkatskaia, E N; Karpenko, V N.

Vrach Delo ; (2): 126-30, 1971.

Article in Russian | MEDLINE | ID: mdl-5099031

Subject(s)

Dinitrophenols/pharmacology , Pesticides/pharmacology , Water-Electrolyte Balance/drug effects , Animals , Potassium/metabolism , Rats , Sodium/metabolism

18.

[Hemopoiesis and the blood clotting system in poisoning with different carbamino pesticides]. / Issledovanie gemopoéza i svertyvaiushchei sistemy krovi pri intoksikatsii nekotorymi karbaminovymi pestitsidami.

Karpenko, V N.

Vrach Delo ; (1): 130-3, 1971 Jan.

Article in Russian | MEDLINE | ID: mdl-5576566

Subject(s)

Blood Coagulation Disorders/chemically induced , Carbamates/toxicity , Hematologic Diseases/chemically induced , Pesticides/toxicity , Sulfides/toxicity , Anemia, Aplastic/chemically induced , Animals , Blood Coagulation/drug effects , Environmental Exposure , Hematopoiesis/drug effects , Leukopenia/chemically induced , Rabbits , Thrombocytopenia/chemically induced

19.

[Several indices of the morphological composition of the blood and natural immunity in healthy white rats]. / Nekotorye pokazateli morfologicheskogo sostava krovi i estestvennogo immuniteta u zdorovykh belykh krys.

Karpenko, V N; Olefir, A I; Moroz, A P.

Lab Delo ; 3: 165-7, 1970.

Article in Russian | MEDLINE | ID: mdl-4195028

Subject(s)

Blood , Immunity , Animals , Blood Bactericidal Activity , Blood Cell Count , Complement System Proteins , Erythrocytes , Female , Hematocrit , Hemoglobins , Male , Osmosis , Phagocytosis , Properdin , Rats

20.

[Changes in certain indices of electrolyte metabolism in poisoning by carbamate pesticides]. / Izmenenie nekotorykh pokazatelei élektrolitnogo obmena pri intoksikatsii karbaminovymi pestitsidami.

Voitenko, G A; Karpenko, V N; Vladimirskaia, A I.

Vrach Delo ; 11: 112-5, 1969 Nov.

Article in Russian | MEDLINE | ID: mdl-5384396

Subject(s)

Carbamates/poisoning , Pesticides/poisoning , Water-Electrolyte Balance , Animals , Female , Hyperkalemia/chemically induced , Hypernatremia/chemically induced , Hypocalcemia/chemically induced , Male , Rats

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