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PLoS One ; 14(5): e0217289, 2019.
Article in English | MEDLINE | ID: mdl-31120971

ABSTRACT

BACKGROUND: Burden, phenotype and risk-factors of lung function defects in successfully treated tuberculosis cases are unclear. METHODS: We performed spirometry with bronchodilators in new drug-sensitive adult (≥18 years) pulmonary tuberculosis cases during the 12 months following successful treatment in India. Airflow obstruction was defined as pre-bronchodilator FEV1/FVC<5th percentile of Global Lung Initiative mixed-ethnicity reference (lower limit of normal [LLN]). Chronic obstructive pulmonary disease (COPD) was defined as post-bronchodilator FEV1/FVC

Subject(s)
Pulmonary Disease, Chronic Obstructive/etiology , Respiration Disorders/etiology , Tuberculosis, Pulmonary/complications , Tuberculosis, Pulmonary/physiopathology , Adult , Cohort Studies , Female , Forced Expiratory Volume , Humans , India , Male , Prospective Studies , Pulmonary Disease, Chronic Obstructive/physiopathology , Respiration Disorders/physiopathology , Risk Factors , Spirometry , Tuberculosis, Pulmonary/drug therapy , Vital Capacity , Young Adult
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