ABSTRACT
Blood plasma uric acid and urea content and aspartate aminotransferase activity were studied in 177 patients with ischemic heart disease and essential hypertension. It was established that the blood uric acid level did not depend essentially on the transamination processes in patients with ischemic heart disease but was closely connected with transamination processes and amino acid metabolism in patients with essential hypertension.
Subject(s)
Alanine Transaminase/blood , Aspartate Aminotransferases/blood , Coronary Disease/blood , Hypertension/blood , Uric Acid/blood , Adult , Aged , Coronary Disease/urine , Humans , Hypertension/urine , Male , Middle Aged , Urea/blood , Uric Acid/urineSubject(s)
Hemodynamics/physiology , Homeostasis/physiology , Kidney/physiology , Puberty/physiology , Anthropometry , Child , Female , Humans , Male , Prognosis , Puberty/blood , Sex CharacteristicsABSTRACT
The content of uric acid in blood plasma has been determined and its relation with the homeostatic renal function has been studied in CHD and hypertensive patients. The attenuation of renal filtration processes has been revealed in a half of the 117 patients. The CHD patients have showed a significant relation between the levels of uric acid and protein in blood. There is an immediate correlation between the uric acid content and alpha 2-globulins in patients with CHD and hyperuricemia. It has been suggested that the development of hyperuricemia in CHD patients is dut to the mechanism of disturbances in binding of uric acid to transport blood proteins.