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Klin Khir ; (2): 52-6, 2011 Feb.
Article in Ukrainian | MEDLINE | ID: mdl-21548331

ABSTRACT

Pathogenetically substantiated approach, using surgical, laser and echosclerosing methods, was applied for improvement of the treatment results in patients, suffering venous forms of the inborn vascular malformations of the lower extremities. The results of examination and treatment in 2006-2009 period were analyzed in 98 patients. The stem malformations with superficial venous system affection was diagnosed in 59 (60.2%) patients, the same with a deep venous system affection--in 27 (27.6%), the extrastem affections--in 7 (7.1%) and the combined malformations--in 5 (5.1%). There was differential tactics of the surgical treatment used together with combination of original surgical procedures, newest laser methods and sclerotherapy, which have permitted to achieve satisfactory late results in 73 (74.5%) patients. Poor results in 25 (25.5%) patients were caused by the pathological process spread and proliferative activity of malformation, what was confirmed by immunohistochemical and morphological investigations data.


Subject(s)
Lower Extremity/blood supply , Vascular Malformations , Vascular Surgical Procedures/methods , Veins/abnormalities , Adolescent , Adult , Child , Endothelium, Vascular/metabolism , Endothelium, Vascular/pathology , Endovascular Procedures/methods , Female , Humans , Laser Coagulation/methods , Lower Extremity/diagnostic imaging , Lower Extremity/surgery , Male , Muscle, Smooth, Vascular/diagnostic imaging , Muscle, Smooth, Vascular/pathology , Muscle, Smooth, Vascular/surgery , Proliferating Cell Nuclear Antigen/biosynthesis , Regional Blood Flow/physiology , Sclerotherapy/methods , Treatment Outcome , Ultrasonography , Vascular Endothelial Growth Factor Receptor-2/biosynthesis , Vascular Malformations/diagnostic imaging , Vascular Malformations/pathology , Vascular Malformations/surgery , Veins/diagnostic imaging , Veins/pathology , Veins/surgery , Young Adult
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