ABSTRACT
The lecture covers one of the most perspective directions in clinical cytology. The emergence of liquid cytology is related to preparation of thin-layer specimens of organism liquids. Nowadays, the liquid cytology spreads more and more due to eephi application in different areas of cytological diagnostics, including screening of cervix uteri diseases, automatic screening, punctate tests, endoscopic and other materials. The lecture presents the basics of method, the characteristics of pre-analytic stage, the approaches to preparation of cytological specimens and cell blocks. The main possibilities, characteristics and perspectives of liquid cytology on the stage of rapid development of molecular genetic studies are discussed.
Subject(s)
Body Fluids/cytology , Cytodiagnosis/methods , Cytological Techniques/methods , Uterine Cervical Neoplasms/diagnosis , Vaginal Smears/methods , Centrifugation , Cytodiagnosis/instrumentation , Cytological Techniques/instrumentation , Female , Humans , Pregnancy , Pregnancy Complications, Neoplastic/diagnosis , Uterine Cervical Diseases/diagnosisABSTRACT
The lecture is devoted to the urgent problem that is to increase the quality of cytological diagnosis, by diminishing the subjectivism factor via introduction of up-to-date computer information technologies into a cytologist's practice. Its main lines from the standardization of cytological specimen preparation to the registration of a cytologist's opinion and the assessment of the specialist's work quality at the laboratories that successfully use the capacities of the current information systems are described. Information technology capabilities to improve the interpretation of the cellular composition of cytological specimens are detailed.
