ABSTRACT
The experimental and clinical study of the allergen diagnostic properties of new Brucella protein-polysaccharide antigen in comparison with brucellin has been made in the leukocyte migration inhibition test, and its working doses have been determined. The results thus obtained suggest that Brucella protein-polysaccharide antigen has considerable diagnostic advantages over commercial brucellin, which presents vast possibilities of using this antigen for the allergen diagnosis of brucellosis in the leukocyte migration inhibition test.
Subject(s)
Allergens , Antigens, Bacterial/immunology , Bacterial Proteins , Brucella abortus/immunology , Brucellosis/diagnosis , Polysaccharides, Bacterial , Animals , Cell Migration Inhibition , Dose-Response Relationship, Immunologic , Drug Evaluation , Drug Evaluation, Preclinical , Female , Guinea Pigs , Humans , Leukocytes/immunology , MaleABSTRACT
Four methods of nephrotomy different in the means of suturing the operation wound of the kidney were studied in experiments in dogs (1--the interrupted suture with the involvement of a wide layer of the parenchyma; 2--the interrupted V-suture with the topical picture of the vessels taken into consideration; 3--the interrupted suture with the topical picture of the vessels taken into consideration; 4--the interrupted suture with hemostasis in the wound). The advantages of the 3d and 4th techniques are shown.
Subject(s)
Kidney/surgery , Animals , Child , Dogs , Evaluation Studies as Topic , Humans , Kidney/blood supply , Kidney/pathology , Kidney Calculi/surgery , Methods , Necrosis , Postoperative Period , Sclerosis , Suture Techniques , Wound HealingABSTRACT
The results of clinical observation on 68 recurrent cases of brucellosis, occurring a long time (3 to 30 years) after the primary disease, are presented. As the recurrent disease developed against an unfavorable premorbid background, a considerable severity in the clinical manifestations of brucellosis was observed.
