Cytomegalovirus Duodenitis Causing Persistent Hypoalbuminemia and Ascites After Liver Transplantation.

A 44-year-old male had persistent hypoalbuminemia and ascites after liver transplantation. Imaging of the liver and gastrointestinal system was normal. Urine examination was negative for proteinuria. A diagnosis of protein-losing enteropathy was suspected, and a duodenal biopsy was done. Duodenal biopsy was positive for cytomegalovirus (CMV). The patient improved with CMV treatment.

Guillain-Barré syndrome: rare extra-intestinal manifestation of hepatitis B.

Extrahepatic syndromes are uncommon manifestations of acute and chronic hepatitis B. The pathogenesis likely involves an aberrant immunologic response to extrahepatic viral proteins. Antiviral therapy reduces the availability of these viral protein antigens and thus halts immune activation. Approximately 1% of all cases of acute inflammatory demyelinating polyneuropathy are associated with hepatitis B. Guillain-Barre syndrome (GBS) is a remarkably clinically diverse disorder with distinctive variants characterised by an immune-mediated attack to components of the peripheral nervous system. In this report, we present a rare case of GBS with chronic hepatitis B that resolved with antiviral and intravenous immunoglobulin therapy.

Knowledge sharing in a health infomediary: role of self-concept, emotional empowerment, and self-esteem.

Health infomediary systems are emerging as important knowledge sharing platforms that help patients manage their own health outside of traditional health care delivery models. Patients participate in health infomediaries to learn from other patients' experiences and knowledge. Knowledge sharing is an important aspect of the success of a health infomediary. Factors related to self-concept have been widely studied in the domains of psychiatry and psychology, in settings such as mental health and behavioural well-being, but remain unexplored in the digital health context. In particular, it is not known how self-concept influences knowledge sharing behaviours in health infomediaries. This study posits that self-efficacy, social identity, and self-stigma drive knowledge sharing in an infomediary through emotional empowerment and appearance-contingent self-esteem. We use the health belief model as a foundation to propose a two-stage model and testable hypotheses. We used secondary archival data of 222 patients participating in a health infomediary specialising in reconstructive surgery. Analyses using structural equation modelling and econometric methods support the hypotheses. Findings broadly suggest that there are distinct paths through emotional empowerment and appearance-contingent self-esteem that can motivate users to contribute knowledge in health infomediaries. We explain the managerial insights and contributions of our study.