ABSTRACT
As many as 120 neonates and their mothers presenting with persistency of cytomegaly virus were studied for impact of maternal specific antibodies to cytomegaly virus on rhe pattern of clinical adaptation in children. 90% of children born of infected mothers display neurologic disturbances, 71.4% have jaundice accompanied by hyperbilirubinemia, 4.7% present with hemorrhagic syndrome. 11 neonates were diagnosed as having cytomegaloviral infection, four such diagnoses were made in a pathoanatomical setting. Thus, the studies made suggest that cytomegaly virus might be neurotrophic and that maternal specific antibodies have negative impact on postnatal adaptation of neonates.
Subject(s)
Adaptation, Physiological/immunology , Cytomegalovirus Infections/immunology , Pregnancy Complications, Infectious/immunology , Adult , Antibodies, Viral/blood , Antibody Specificity , Cytomegalovirus/immunology , Cytomegalovirus Infections/congenital , Cytomegalovirus Infections/physiopathology , Female , Humans , Infant, Newborn , PregnancyABSTRACT
Results of dynamic microbiological control and clinical observation in specialized departments of newborns pathologies and nursing of premature children for 1989-1994 are presented. Criteria of gastrointestinal colonization, clinical and bacteriological indices of the risk of appearance of suppurative-septic infections in newborns, the leading role of gram-negative bacteria and the increasing role of staphylococci in the development of these infections have been established. Sensitivity of the hospital strains of microorganisms isolated from newborns and from the environment to antibacterial preparations has been studied. Their multiple drug resistance and uniformity according to antibiotic program which permits supposing intrahospital origin of these strains has been established.