ABSTRACT
UNLABELLED: Multiple sclerosis (SM) is an idiopathic, demyelinating CNS disease, with often ocular manifestations. Besides the most common SM ocular manifestation-optic neuritis, particular attention should be paid to uveitis. It is estimated that uveitis is ten times more frequent in population with SM than on population without it. PURPOSE: The aim of this study is to present our own observation of clinical course of the uveitis in SM patients. MATERIAL AND METHODS: We studied 9 patients (7 women and 2 men), who had been treated in 2nd Department of Ophthalmology Lublin Medical School in 1993-2006. In I group (2 persons) uveitis was casually diagnosed during an ophthalmic examination in patients with SM. In II group (2 persons), first event of the uveitis was observed in patients with already diagnosed SM. In III group (2 persons), initial diagnose was uveitis, and subsequently SM was diagnosed. Group IV consisted of patients with uveitis, who developed SM several years later (3 persons). RESULTS: Clinical course of inflammatory process was bilateral, severe and chronic with exacerbation. Panuveitis, cystoid macular oedema, cataract formation, and glaucoma were the most often findings. All of patients were treated with corticosteroids. Therapy with corticosteroids caused improvement in all patients. CONCLUSIONS: The possibility of co-existence of SM and uveitis should be emphasized. Corticosteroids are efficient in the treatment of ocular complications in patients with SM.
Subject(s)
Glucocorticoids/administration & dosage , Multiple Sclerosis/complications , Uveitis/diagnosis , Uveitis/drug therapy , Adolescent , Adult , Female , Humans , Male , Poland , Risk Factors , Treatment Outcome , Uveitis/etiology , Visual Acuity , Young AdultABSTRACT
PURPOSE: The aim of our work is to present clinical and histological data of the case of severe sympathetic ophthalmia (SO). Sympathetic ophthalmia is a rare, bilateral, non-necrotizing granulomatous panuveitis that follows penetrating injury to one eye. SO is a potentially blinding condition. MATERIAL AND METHODS: A 40-year-old man sustained a penetrating injury to his right eye. He refused to be treated surgically. A few days later, he developed bacterial endophthalmitis. After 5 months the patient came to our hospital with clinical manifestations suggesting SO. His right eye was removed. Unfortunately, despite the intensive pharmacological treatment the uveitis of the left eye intensified. RESULTS: Generalized uveitis with optic nerve oedema, secondary cataract and glaucoma resulted in total blindness. CONCLUSIONS: Although, SO is a rare disease, ophthalmologists should be aware of its devastating effect on vision.
Subject(s)
Eye Injuries, Penetrating/complications , Ophthalmia, Sympathetic/diagnosis , Ophthalmia, Sympathetic/etiology , Adult , Edema/etiology , Endophthalmitis/etiology , Humans , Male , Ophthalmia, Sympathetic/pathology , Optic Nerve Diseases/etiology , Rare Diseases , Uveitis/etiologyABSTRACT
PURPOSE: The main purpose of the study is the evaluation of the dependence between lens thickness in eyes with cataract and glaucoma and the intraocular pressure after cataract extraction with posterior chamber lens implantation. MATERIAL AND METHODS: 138 eyes with cataract and glaucoma were examined. Patients were divided into three groups according to the type of glaucoma: I open angle glaucoma II closed angle glaucoma III glaucoma with pseudoexfoliation syndrome All patients received preoperatively drugs reducing intraocular hypertension. The intraocular pressure was measured on operation day and on the first and fifth day after. The subsequent measurements were carried out one month, 3 months and nine months postoperatively. Lens thickness measurement was conducted with ultrasonography one day before operation. RESULTS: The dependence between lens thickness and intraocular pressure normalization (p < 0.005) has been found on the basis of statistical research with t-Student test in the closed angle glaucoma group with the greatest preoperative lens thickness. CONCLUSIONS: The statistically proven dependence between preoperative lens thickness and postoperative intraocular pressure reduction in patients with the closed angle glaucoma, has been found on the basis of conducted research.
Subject(s)
Cataract/complications , Cataract/physiopathology , Glaucoma/physiopathology , Intraocular Pressure , Lenses, Intraocular , Aged , Cataract Extraction , Exfoliation Syndrome/physiopathology , Female , Follow-Up Studies , Glaucoma/complications , Glaucoma/surgery , Glaucoma, Angle-Closure/physiopathology , Glaucoma, Open-Angle/physiopathology , Humans , Male , Middle Aged , Time Factors , Visual AcuityABSTRACT
PURPOSE: This study presents the case history of a 58-year-old woman with a diagnosed spontaneous carotid-cavernous fistula on the left side and mild hypertension. THE FIRST SIGNS OF THIS DISEASE WERE: Headache, double vision, proptosis, ptosis of the left upper lid, paresis of the left abducens nerve, conjunctival edema, dilatation and tortuosity of the vessels in conjunctiva and episclera. In the course of this disease a massive central retinal vein occlusion occurred in the left eye. The angiography demonstrated carotid-cavernous fistula on the left side with pathological blood flow. Embolization of the fistula was attempted, but it was not successful. During 6 months of follow up, the signs of central retinal vein occlusion and other manifestations disappeared. CONCLUSIONS: A spontaneous carotid-cavernous fistula should be considered as one of the contributing factors of the central retinal vein occlusion, particularly in menopausal women with concomitant arterial hypertension. The significant reduction of neurological and ophthalmological symptoms and signs may suggest, that arteriovenous shunt is closed.
