1.
J Am Chem Soc
; 143(12): 4543-4549, 2021 Mar 31.
Article
in English
| MEDLINE
| ID: mdl-33729786
ABSTRACT
We report here a C-H homoallylation reaction of aromatic ketones with methylenecyclopropanes (MCPs) only using a catalytic amount of Fe(PMe3)4. A variety of aromatic ketones and MCPs are applicable to the reaction to form ortho-homoallylated aromatic ketones selectively via regioselective scission of the three-membered rings. The homoallylated products are amenable to further elaborations, providing functionalized 1,2-dihydronaphthalenes.