ABSTRACT
Eccrine angiomatous hamartoma is a rare hamartoma that usually affects childhood and adolescence. In this report we describe a typical onset and clinical presentation of eccrine angiomatous hamartoma. Histopathological analysis and immunohistochemical staining of the sections were done to confirm the diagnosis.
ABSTRACT
Congenital self-healing reticulohistiocytosis, also known as Hashimoto-Pritzker disease, is a single system Langerhans cell histiocytosis that typically presents in healthy newborns and spontaneously regresses. In the present report, we described a 2-month-old Thai female newborn with multiple hypopigmented flat-topped papules without any internal organ involvement including normal blood cell count, urinary examination, liver and renal functions, bone scan, chest X-ray, abdominal ultrasound, and bone marrow biopsy. The histopathology revealed typical findings of Langerhans cell histiocytosis, which was confirmed by the immunohistochemical staining CDla and S100. Our patient's lesions had spontaneously regressed within afew months, and no new lesion recurred afterfour months follow-up.
Subject(s)
Histiocytosis, Langerhans-Cell/diagnosis , Skin Diseases, Papulosquamous/diagnosis , Biopsy , Diagnosis, Differential , Female , Histiocytosis, Langerhans-Cell/congenital , Histiocytosis, Langerhans-Cell/pathology , Humans , Hypopigmentation/congenital , Hypopigmentation/diagnosis , Hypopigmentation/pathology , Infant , Skin Diseases, Papulosquamous/congenital , Skin Diseases, Papulosquamous/pathologyABSTRACT
Rosai-Dorfminan disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a benign idiopathic proliferative disorder of the histiocyte. Purely Cutaneous Rosai-Dorfman disease (CRDD) is a separated clinical entity without lymph node and organ involvement. The histologic features resemble RDD, but with dermal infiltration. This rare condition is benign and mostly self-limited The authors report a 66-year-old Thai male patient, diagnosed as purely CRDD, with co-existing capillary hemangioma. In addition, we show that the treatment intralesional corticosteroid can produce the remission of the plaque and tumoral types of this condition.
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Hemangioma, Capillary/complications , Hemangioma, Capillary/drug therapy , Histiocytosis, Sinus/complications , Histiocytosis, Sinus/drug therapy , Aged , Biopsy , Humans , Immunohistochemistry , Injections, Intralesional , MaleABSTRACT
Thailand is not an endemic area for leishmaniasis. Several cases of autochthonous visceral leishmaniasis have been reported from Thailand but cutaneous leishmaniasis has never been reported. We reported a three-year-old girl who presented with a chronic ulcer on her cheek which proved to be cutaneous leishmaniasis. The diagnosis was made by finding amastigotes on skin biopsy; the patient had a therapeutic response to itraconazole.
