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J Cutan Pathol ; 39(2): 294-7, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22077555

ABSTRACT

Granulomatous cutaneous reactions are well described in association with T-cell non-Hodgkin lymphoma and Hodgkin lymphoma, but are rarely seen in association with B-cell non-Hodgkin lymphoma or leukemia. We report a case of a 65-year-old woman with B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who presented with multiple, tender, firm pink papules on the face, upper trunk and upper extremities 6 years after diagnosis of CLL. Biopsy revealed both palisading granulomatous dermatitis consistent with actinic granuloma and a dense perivascular lymphocytic infiltrate consistent with the patient's known history of leukemia. This is an unusual manifestation of cutaneous B-cell CLL that is rarely seen.


Subject(s)
Facial Neoplasms/pathology , Granuloma/pathology , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Skin Neoplasms/pathology , Aged , Dermatitis/pathology , Female , Humans
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