1.
J Ethnopharmacol
; 84(2-3): 241-5, 2003 Feb.
Article
in English
| MEDLINE
| ID: mdl-12648821
ABSTRACT
The hypoglycemic activity of lectin isolated from Urtica pilulifera L. seeds (Urticaceae) was investigated in streptozotocin (STZ) induced diabetic rats. Significant hypoglycemic effect was found at the dose of 100 mg/kg after i.p. administration for 30 days. Blood glucose (BG) level, food and fluid intake, body weight (BW) loss and histopathologic findings of the normal and diabetic animals were evaluated. The group treated with UPSL (U. pilulifera seed lectin) was also compared against glipizide (oral antidiabetic agent, Carlo-Erba) as a standard.
Subject(s)
Diabetes Mellitus, Experimental/drug therapy , Hypoglycemic Agents/pharmacology , Urtica dioica/chemistry , Animals , Blood Glucose/metabolism , Body Weight/drug effects , Cell Count , Diabetes Mellitus, Experimental/blood , Diabetes Mellitus, Experimental/pathology , Drinking/drug effects , Eating/drug effects , Islets of Langerhans/drug effects , Islets of Langerhans/pathology , Lectins/chemistry , Lectins/isolation & purification , Lectins/pharmacology , Male , Pancreas/pathology , Rats , Rats, Wistar , Seeds/chemistry
2.
Rev Hist Pharm (Paris)
; 44(312 suppl): 383-4, 1996.
Article
in French
| MEDLINE
| ID: mdl-11618681
Subject(s)
Materia Medica/history , Pharmacies/history , Europe , History, 19th Century , Humans , Turkey
3.
Lloydia
; 36(4): 426, 1973 Dec.
Article
in English
| MEDLINE
| ID: mdl-4797937
