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Int J Gynecol Cancer ; 11(6): 471-4, 2001.
Article in English | MEDLINE | ID: mdl-11906551

ABSTRACT

The aim of this study was to evaluate whether omentectomy, appendectomy, and peritoneal biopsy should be a routine part of staging surgery in endometrial carcinoma. Data of 97 patients who had been diagnosed with clinical stage I endometrial carcinoma were reviewed. Associations in the data obtained, pelvic and para-aortic lymph node status, depth of myometrial invasion, grade, and histology were investigated. The chi-square (chi2) test was used for statistical analysis. Of 97 patients, six (6%) had omental metastases, which was microscopic in four. There was a statistically significant relationship between omental metastasis and tumor grade (P < 0.01). Deep myometrial invasion was significantly more common in patients with omental metastases. Tumor was found in one of 55 appendectomy specimens (2%). Omentectomy may be included in surgical staging in patients with deeply invasive or grade 3 endometrial cancer because of the possibility of omental metastasis in spite of what appears to be stage I disease in laparotomy. In other cases, omentectomy and appendectomy and biopsies from peritoneal sites should be performed in the presence of grossly suspicious disease.


Subject(s)
Adenocarcinoma, Clear Cell/surgery , Adenocarcinoma, Mucinous/surgery , Appendectomy , Cystadenocarcinoma, Serous/surgery , Endometrial Neoplasms/surgery , Omentum/surgery , Peritoneal Cavity/pathology , Adenocarcinoma, Clear Cell/pathology , Adenocarcinoma, Mucinous/pathology , Biopsy , Cystadenocarcinoma, Serous/pathology , Endometrial Neoplasms/pathology , Female , Humans , Lymph Nodes/pathology , Middle Aged , Neoplasm Staging , Risk Factors
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