Subject(s)
Alleles , Ethnicity/genetics , Genetic Variation/genetics , Oxidoreductases/genetics , Gene Frequency/genetics , Genetics, Population/methods , Genetics, Population/statistics & numerical data , Humans , Infant, Newborn , Methylenetetrahydrofolate Dehydrogenase (NAD+) , Models, Genetic , Neonatal Screening/methodsABSTRACT
Studies of prenatal factor effects on the newborns' colloid-osmotic status, a pressing problem in present-day obstetrics, were carried out in 2 groups of women: Group 1 consisted of 50 women with spontaneous delivery and Group 2, also consisting of 50 women, who delivered via cesarean section, 25 of them because of a cicatrix on the uterus and the rest because of severe gestoses characterized by nephropathy and Stage III pre-eclampsia. Blood samples were collected directly after delivery from the mother's vein and from the newborn's umbilical vein, and the colloid-osmotic status of the plasma was analyzed. The results permitted singling out a number of prenatal factors influencing the newborns' colloid-osmotic status. These factors are as follows: obstetrical abnormalities, gestosis among other things; intensive care of the mother during delivery or after surgery, administration of diuretics, delivery mode, etc. These results have brought the authors to a conclusion that standardized infusion therapy without due consideration for the colloid-osmotic status is inadmissible, for it may result in iatrogenic complications in the newborns.
Subject(s)
Cesarean Section , Colloids , Delivery, Obstetric , Infant, Newborn/blood , Adult , Female , Fetal Blood , Humans , Infusions, Parenteral/adverse effects , Osmolar Concentration , PregnancyABSTRACT
The paper addresses fluid therapy after cesarean section in toxemic parturients. A comparative study involved 130 parturients and 540 women with a history of toxemia of pregnancy of variable severity. It was demonstrated that the routine fluid therapy employed in women with mild toxemia was not suitable for parturients with Grade III pregnancy-associated renal disease and preeclampsia. This is explainable by 3 types of abnormality in the colloid oncotic pressure (hyper-, hypo- and normo-osmolar++ dysosmia); most of the patients presented with hypo-osmolar and hypo-oncotic++ plasma states coexisting with impairment of renal excretory and concentrating function.
Subject(s)
Blood Transfusion , Cesarean Section , Erythrocyte Transfusion , Fluid Therapy , Pre-Eclampsia/surgery , Combined Modality Therapy , Female , Humans , Postoperative Care , PregnancyABSTRACT
The paper describes changes in mineral and protein metabolism and renal function in mothers with an uncomplicated ++post-cesarean course. Stress norms of mothers delivered by cesarean section were quantitatively different from those of surgical patients: the former had lower values of osmolality and glucose levels and a marked reduction in total protein and albumin levels. This warrants fluid therapy controlling for the changes induced by the operation.
