1.
NPJ Sci Food
; 7(1): 37, 2023 Jul 21.
Article
in English
| MEDLINE
| ID: mdl-37479699
ABSTRACT
Breeding yeast strains for industrial alcoholic fermentation requires laborious screening due to the lack of in vivo modification strategies. Here we show that quiescence-specific cell wall thickening via synthesis of a major component, 1,3-ß-glucan, critically antagonizes cellular fermentation ability by sequestering the available cytoplasmic carbon sources. This study provides insights into glycolytic control and reports an effective and reliable rational fermentation design.