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Hinyokika Kiyo ; 42(8): 613-6, 1996 Aug.
Article in Japanese | MEDLINE | ID: mdl-8889574

ABSTRACT

Multiple tumors of mediastinum, retroperitoneum and lung were detected in a 40-year-old man presented with lumbago and lower abdominal pain. As biopsy specimen taken from the cervical lymph node suggested germ-cell tumor and his testes were normally palpable, the initial diagnosis was an extragonadal germ-cell tumor. However, since ultrasonography of his left testis showed a small high echoic lesion (5 mm) assumed to be a burned-out tumor, orchiectomy was performed. Histological findings confirmed scar tissue as burned-out tumor and also revealed some malignant cells lining the seminiferous tubules that were thought to be the carcinoma-in-situ of the testis. After chemotherapy of etoposide and cisplatinum he achieved a partial response which has been maintained for 7 months. Examinations for burned-out tumor or carcinoma-in-situ of the testis should be made for the patients with an extragonadal germ cell tumor who have normally palpable testes.


Subject(s)
Carcinoma in Situ/diagnosis , Germinoma/diagnosis , Lung Neoplasms/diagnosis , Mediastinal Neoplasms/diagnosis , Neoplasms, Multiple Primary , Retroperitoneal Neoplasms/diagnosis , Testicular Neoplasms/diagnosis , Adult , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Carcinoma in Situ/therapy , Cisplatin/administration & dosage , Combined Modality Therapy , Diagnosis, Differential , Etoposide/administration & dosage , Germinoma/therapy , Humans , Lung Neoplasms/therapy , Male , Mediastinal Neoplasms/therapy , Orchiectomy , Retroperitoneal Neoplasms/therapy , Testicular Neoplasms/therapy
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