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1.
J Ren Nutr ; 16(3): 229-32, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16825025

ABSTRACT

It is well known that secondary hyperparathyroidism may be an extremely severe condition in chronic renal failure, and almost all patients with chronic kidney disease, even in the well-developed countries, encounter every kind of bone abnormalities if they are not treated properly. Although some sporadic cases have been reported of unique facial bone changes, the largest collection of this phenomenon has been reported by Sagliker et al. We also have found 6 of 9 patients who have these changes (Sagliker syndrome) to manifest class II malocclusion of the upper and lower jaws according to dental universally accepted criteria by performing cephalometric studies, x-ray plain films, tomographic procedures, and drawing technology.


Subject(s)
Bone Diseases/etiology , Cephalometry , Facial Bones , Hyperparathyroidism, Secondary/complications , Kidney Failure, Chronic/complications , Adolescent , Adult , Female , Humans , Male , Malocclusion, Angle Class II/diagnosis , Malocclusion, Angle Class II/epidemiology , Syndrome
2.
J Ren Nutr ; 16(3): 233-6, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16825026

ABSTRACT

Patients with chronic renal failure (CRF) often have signs and symptoms related to fluid and electrolyte disturbances, anemia, malnutrition, bone disease, and gastrointestinal problems. Vascular and neurologic impairment in particular remain an important source of morbidity and mortality in this vulnerable patient population. Sagliker syndrome is a novel syndrome that was recently described in 2004 in patients with CRF and severe and late secondary hyperparathyroidism who suffered from severe skull and facial bone changes, particularly from uglifying human face appearances and neuropsychiatric disorders. The goal of this study was to assess neuropsychiatric manifestations occurring in CRF patients with Sagliker syndrome. Four female and 8 male patients with CRF on regular dialysis at the hemodialysis units of the Internal Medicine Departments around southern Turkey participated in the study. All patients underwent a clinical neurologic examination performed by the same neurologist. Neuropsychiatric signs and symptoms were found in all cases. The results showed that the most frequent neurologic manifestations in CRF patients with Sagliker syndrome were headache, polyneuropathy, cranial neuropathy, fatigue, and psychiatric disorders.


Subject(s)
Bone Diseases/complications , Facial Bones , Hyperparathyroidism, Secondary/complications , Kidney Failure, Chronic/complications , Nervous System Diseases/epidemiology , Adolescent , Adult , Cranial Nerve Diseases/epidemiology , Fatigue , Female , Headache/epidemiology , Humans , Kidney Failure, Chronic/therapy , Male , Mental Disorders/epidemiology , Nervous System Diseases/complications , Nervous System Diseases/diagnosis , Polyneuropathies/epidemiology , Renal Dialysis , Syndrome
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