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Eur Psychiatry ; 30(1): 94-8, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25172156

ABSTRACT

Face memory deficits may be a bipolar disorder (BD) endophenotype. BD (n=27) and unaffected youth at risk (n=13) exhibited middle frontal gyrus hypoactivation during successful vs. unsuccessful encoding. Parahippocampal gyrus dysfunction was found in BD and at-risk youth (vs. low-risk, n=37). Middle occipital gyrus hypoactivation was only present in BD.


Subject(s)
Bipolar Disorder/physiopathology , Bipolar Disorder/psychology , Brain/physiopathology , Emotions , Facial Expression , Magnetic Resonance Imaging , Adolescent , Endophenotypes , Female , Frontal Lobe/physiopathology , Humans , Male , Memory , Occipital Lobe/physiopathology , Parahippocampal Gyrus/physiopathology , Risk
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