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Farmakol Toksikol ; 50(1): 89-91, 1987.
Article in Russian | MEDLINE | ID: mdl-3556561

ABSTRACT

Blood serum theophylline concentrations were studied in 6 volunteers and 8 patients with bronchospastic syndrome by using an enzyme immunological assay with a commercial kit "Fedesim" (USA) at intravenous and oral administration of euphylline in a dose of 5 mg/kg. The maximal concentration at intravenous injection of euphylline was reached in volunteers in 15 minutes, at oral administration--in 90 minutes, and in patients--somewhat later.


Subject(s)
Theophylline/blood , Adult , Aminophylline/administration & dosage , Aminophylline/blood , Bronchial Spasm/blood , Bronchial Spasm/drug therapy , Female , Humans , Kinetics , Male , Middle Aged , Smoking , Solutions , Tablets , Time Factors
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