Long-term vision outcomes and breed differences of Ahmed Glaucoma Valve implantation in 132 eyes of 122 dogs.

OBJECTIVE: To evaluate the long-term vision outcomes of Ahmed glaucoma valve (AGV) implantation in dogs. PROCEDURES: The medical records of dogs that underwent AGV implantation from January 2010 to December 2019 were reviewed to assess the duration of post-surgical vision preservation (PVP). The relationship between PVP and the underlying cause of glaucoma, implant placement, and preoperative intraocular pressure was evaluated. RESULTS: One hundred and thirty-two eyes of 122 dogs (mean age, 8.3 ± 2.6 years) were included. The mean ± standard error of PVP for all eyes was 57.5 ± 3.9 months. PVP in the dogs with primary acute glaucoma and prior history of cataract surgery was 56.4 ± 4.7 and 59.3 ± 5.9 months, respectively (p = .712). The PVP of the Shiba Inu, American Cocker Spaniel, and other breeds was 63.1 ± 5.5, 33.7 ± 5.3, and 59.1 ± 6.3 months, respectively (p < .05). The PVP in dogs with medial implantation was 61.9 ± 4.7 months, and in those with lateral implantation was 45.4 ± 6.4 months (p = .034). Among the 132 eyes investigated, 48 (36.4%) lost vision by the last follow-up, and 18 eyes retained vision for more than 5 years. Two of the total number of eyes retained their vision for more than 8 years. CONCLUSIONS: The vision outcomes regarding the use of AGV for the management of canine glaucoma were favorable in dogs.

Breed prevalence of canine ulcerative keratitis according to depth of corneal involvement.

OBJECTIVE: To investigate the breed prevalence of canine ulcerative keratitis (UK) according to the depth of corneal involvement. PROCEDURES: Dogs diagnosed with ulcerative keratitis from 2008 to 2017 at the Triangle Animal Eye Clinic were included in this study. Only breeds with more than 20 eyes affected were selected. UK lesions were classified as superficial (Grade 1), stromal (Grade 2) or descemetoceles and perforations (Grade 3) and compared between brachycephalic (BC) and non-BC dog breeds. RESULTS: Of 8877 dogs evaluated at Triangle Animal Eye Clinic from 2008 to 2017, 1109 eyes of 1018 dogs (male, 326 eyes; neutered male, 253 eyes; female, 211 eyes; spayed female, 316 eyes; and unknown sex, 3 eyes) aged between 0.1 and 19.2 years (mean ± standard deviation [SD], 8.33 ± 4.24 years) were diagnosed with UK. The number of eyes that was classified as Grade 1 was 359 eyes (187 non-BC and 172 BC), Grade 2 was 373 eyes (60 non-BC and 313 BC) and Grade 3 was 377 eyes (47 non-BC and 330 BC). Significant differences were observed between BC and non-BC dogs for all grades of UK. BC dogs were significantly more frequently affected by Grades 2 and 3 and less frequently by Grade 1 UK (P < .01). French bulldogs are more likely to be affected with Grade 1. CONCLUSIONS: Brachycephalic dogs are more likely to have deeper corneal involvement in UK. This study provides novel data on the prevalence of superficial UK, which was low in BC dogs and high in non-BC breeds.

A novel strip meniscometry method for measuring aqueous tear volume in dogs: Clinical correlations with the Schirmer tear and phenol red thread tests.

OBJECTIVES: The strip meniscometry test (SMT) is a novel method for quantitative measurement of tear volume with only five seconds. We aimed to evaluate clinical correlations of SMT with the gold standard Schirmer tear test (STT) and phenol red thread test (PRT) in dogs, including normal and tear-deficient eyes. ANIMALS STUDIED: Left eyes from 621 outpatient dogs with and without ocular disorders were evaluated. PROCEDURES: Each subject underwent SMT, PRT, and STT without topical anesthesia in the described order with five-minute intervals. The total population was divided into four groups by classifying tear deficiency severity based on STT results: "severe" (0-5 mm/min), "moderate" (6-10 mm/min), "subclinical" (11-14 mm/min), and "normal" (15 or more mm/min). RESULTS: The strongest correlation coefficient was found between SMT-STT (0.676), followed by PRT-STT (0.637) and SMT-PRT (0.600) pairs. Mean(SD) scores of SMT, PRT, and STT in total population were 9.47 (4.08) mm/5 s, 33.30 (8.52) mm/15 s, and 16.47 (7.01) mm/min. Significant differences were found among STT-classified groups, both using SMT and PRT results. Receiver operating characteristic (ROC) curves revealed that SMT better agreed with STT than PRT; agreement increased with increasing STT severity. A cutoff for SMT was identified at 10 mm/5 s to discriminate normal eyes from tear-deficient eyes, yielding high sensitivities and acceptable specificities. CONCLUSIONS: SMT could be superior to PRT for discriminating tear-deficient eyes. The high sensitivity of SMT could be useful as an initial diagnostic tool to rule out normal eyes with the short testing time.